Autoantibodies and infection with SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies

Jan Damoiseaux; Arad Dotan; Marvin J Fritzler; Dimitrios P Bogdanos; Pier Luigi Meroni; Dirk Roggenbuck; Michel Goldman; Nils Landegren; Paul Bastard; Yehuda Shoenfeld; Karsten Conrad

doi:10.1016/j.autrev.2021.103012

Autoantibodies and infection with SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies

Jan Damoiseaux^*, Arad Dotan, Marvin J Fritzler, Dimitrios P Bogdanos, Pier Luigi Meroni, Dirk Roggenbuck, Michel Goldman, Nils Landegren, Paul Bastard, Yehuda Shoenfeld, Karsten Conrad

^*Corresponding author for this work

Research output: Contribution to journal › (Systematic) Review article › peer-review

Abstract

The relation between infections and autoimmune diseases has been extensively investigated. Multiple studies suggest a causal relation between these two entities with molecular mimicry, hyperstimulation and dysregulation of the immune system as plausible mechanisms. The recent pandemic with a new virus, i.e., SARS-CoV-2, has resulted in numerous studies addressing the potential of this virus to induce autoimmunity and, eventually, autoimmune disease. In addition, it has also revealed that pre-existing auto-immunity (auto-Abs neutralizing type I IFNs) could cause life-threatening disease. Therefore, the topic of the 15th Dresden Symposium on Autoantibodies was focused on autoimmunity in the SARS-CoV-2 era. This report is a collection and distillation of the topics presented at this meeting.

Original language	English
Article number	103012
Number of pages	8
Journal	Autoimmunity Reviews
Volume	21
Issue number	3
Early online date	9 Dec 2021
DOIs	https://doi.org/10.1016/j.autrev.2021.103012
Publication status	Published - Mar 2022

Keywords

Anti-IFNa
Antiphospholipid syndrome
Autoantibodies
Autoimmunity
COVID-19
MIS-C
Molecular mimicry
SARS-CoV-2
SILICONE BREAST

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10.1016/j.autrev.2021.103012Licence: CC BY

Cite this

Damoiseaux, J., Dotan, A., Fritzler, M. J., Bogdanos, D. P., Meroni, P. L., Roggenbuck, D., Goldman, M., Landegren, N., Bastard, P., Shoenfeld, Y., & Conrad, K. (2022). Autoantibodies and infection with SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies. Autoimmunity Reviews, 21(3), Article 103012. https://doi.org/10.1016/j.autrev.2021.103012

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title = "Autoantibodies and infection with SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies",

abstract = "The relation between infections and autoimmune diseases has been extensively investigated. Multiple studies suggest a causal relation between these two entities with molecular mimicry, hyperstimulation and dysregulation of the immune system as plausible mechanisms. The recent pandemic with a new virus, i.e., SARS-CoV-2, has resulted in numerous studies addressing the potential of this virus to induce autoimmunity and, eventually, autoimmune disease. In addition, it has also revealed that pre-existing auto-immunity (auto-Abs neutralizing type I IFNs) could cause life-threatening disease. Therefore, the topic of the 15th Dresden Symposium on Autoantibodies was focused on autoimmunity in the SARS-CoV-2 era. This report is a collection and distillation of the topics presented at this meeting.",

keywords = "Anti-IFNa, Antiphospholipid syndrome, Autoantibodies, Autoimmunity, COVID-19, MIS-C, Molecular mimicry, SARS-CoV-2, SILICONE BREAST",

author = "Jan Damoiseaux and Arad Dotan and Fritzler, {Marvin J} and Bogdanos, {Dimitrios P} and Meroni, {Pier Luigi} and Dirk Roggenbuck and Michel Goldman and Nils Landegren and Paul Bastard and Yehuda Shoenfeld and Karsten Conrad",

year = "2022",

month = mar,

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Damoiseaux, J, Dotan, A, Fritzler, MJ, Bogdanos, DP, Meroni, PL, Roggenbuck, D, Goldman, M, Landegren, N, Bastard, P, Shoenfeld, Y & Conrad, K 2022, 'Autoantibodies and infection with SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies', Autoimmunity Reviews, vol. 21, no. 3, 103012. https://doi.org/10.1016/j.autrev.2021.103012

Autoantibodies and infection with SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies. / Damoiseaux, Jan; Dotan, Arad; Fritzler, Marvin J et al.
In: Autoimmunity Reviews, Vol. 21, No. 3, 103012, 03.2022.

Research output: Contribution to journal › (Systematic) Review article › peer-review

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AU - Bogdanos, Dimitrios P

AU - Meroni, Pier Luigi

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