Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Post-Operative Atrial Fibrillation

Jordi Heijman, Azinwi Phina Muna, Tina Veleva, Cristina E Molina, Henry Sutanto, Marcel A Tekook, Qiongling Wang, Issam Abu-Taha, Marcel Gorka, Stephan Künzel, Ali El-Armouche, Hermann Reichenspurner, Markus Kamler, Viacheslav O Nikolaev, Ursula Ravens, Na Li, Stanley Nattel, Xander Ht Wehrens, Dobromir Dobrev*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1036-1055
Number of pages20
JournalCirculation Research
Volume127
Issue number8
DOIs
Publication statusPublished - 25 Sep 2020

Keywords

  • action potentials
  • atrial fibrillation
  • calcium
  • CaMKII
  • interleukin
  • NLRP3
  • sarcoplasmic reticulum
  • SARCOPLASMIC-RETICULUM
  • CARDIAC-SURGERY
  • CALCIUM-RELEASE
  • UP-REGULATION
  • CA2+ LEAK
  • INFLAMMATION
  • FIBROSIS
  • ONSET
  • CHANNELS
  • PROTEIN

Cite this

Heijman, J., Muna, A. P., Veleva, T., Molina, C. E., Sutanto, H., Tekook, M. A., Wang, Q., Abu-Taha, I., Gorka, M., Künzel, S., El-Armouche, A., Reichenspurner, H., Kamler, M., Nikolaev, V. O., Ravens, U., Li, N., Nattel, S., Wehrens, X. H., & Dobrev, D. (2020). Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Post-Operative Atrial Fibrillation. Circulation Research, 127(8), 1036-1055. https://doi.org/10.1161/CIRCRESAHA.120.316710