Abstract
Background:Increased central (or abdominal) fat mass has been associated with cardiometabolic risk factors such as high low-density lipoproteins (LDL)-cholesterol or triglycerides (TG) concentration in children. Objectives:To generate pediatric reference centiles for trunk/leg fat mass ratio (T2L) (assessed by dual-energy X-ray absorptiometry [DXA]) and to evaluate the association of LDL-cholesterol and TG concentrations with T2L in children and adolescents.Methods:Data of the National Health and Nutrition Examination Survey (1999-2004) were used to determine total and regional fat mass by DXA of the participants (aged 8-19 years) who had also an examination of LDL-cholesterol and TG concentrations. Fat mass was assessed by DXA-determined fat mass index (FMI). Central fat mass was quantified by T2L. Results:The DXA results of 6538 children and adolescents (2629 females) were used to generate reference centiles for T2L. In girls, T2L was significantly associated with high LDL-cholesterol and TG concentration (odds ratio [OR] adjusted to FMI 1.69), (95% confidence interval [CI] 1.20-2.40), and 1.45 (95% CI 1.11-1.91,p = 0.003 andp = 0.008). In boys, T2L was significantly associated only with high TG concentration (OR adjusted to FMI 1.81 [95% CI 1.52-2.19,p < 0.001]). Conclusions:A central fat distribution seemed to be an independent risk factor for high TG concentrations in children and for high LDL-cholesterol only in girls. The first ethnicity-specific, pediatric reference centiles for T2L were presented.
Original language | English |
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Pages (from-to) | 428-439 |
Number of pages | 12 |
Journal | Childhood obesity |
Volume | 16 |
Issue number | 6 |
DOIs | |
Publication status | Published - 1 Sept 2020 |
Keywords
- abdominal fat
- body-fat
- cardiometabolic risk-factors
- central adiposity
- cholesterol concentration
- indian children
- insulin sensitivity
- leg fat mass ratio
- low-density lipoproteins
- metabolic risk
- reference centiles
- resistance exercise
- sex-differences
- to-height ratio
- triglycerides concentration
- trunk
- waist circumference
- INDIAN CHILDREN
- CARDIOMETABOLIC RISK-FACTORS
- BODY-FAT
- RESISTANCE EXERCISE
- TO-HEIGHT RATIO
- ABDOMINAL FAT
- INSULIN SENSITIVITY
- WAIST CIRCUMFERENCE
- METABOLIC RISK
- SEX-DIFFERENCES