Assisted Reproductive Technologies

Astrid E.P. Cantineau; Cato J. Vrouwenraets; Aafke P.A. van Montfoort

doi:10.1007/978-3-030-84725-8_33

Assisted Reproductive Technologies

Astrid E.P. Cantineau^*, Cato J. Vrouwenraets, Aafke P.A. van Montfoort

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic

Abstract

Since the birth of Louise Brown, the first “test tube baby, " in 1978, assisted reproductive technology (ART) has been widely implemented as a standard treatment for couples with subfertility problems. An estimated 8 million children have been born via ART worldwide and up to 6% of newborns in Europe and 1.5% in United States are conceived via this technique [2]. ART pregnancies are at an increased risk for neonatal complications such as preterm birth and low birth weight as well as maternal complications such as gestational diabetes and preeclampsia. The exact mechanism behind the adverse outcomes is not known, but a role for the placenta is likely. In this chapter we will summarize current knowledge on human placenta development and functioning in relation to ART treatments. We will focus on morphology, vascularization, immunology, placental biomarkers, and aneuploidies.

Original language	English
Title of host publication	Benirschke’s Pathology of the Human Placenta: Seventh Edition
Editors	Rebecca N. Baergen, Graham J. Burton, Cynthia G. Kaplan
Publisher	Springer International Publishing
Pages	887-900
Number of pages	14
Edition	7
ISBN (Electronic)	9783030847258
ISBN (Print)	9783030847241
DOIs	https://doi.org/10.1007/978-3-030-84725-8_33
Publication status	Published - 1 Jan 2021

Keywords

ART
Confined placental mosaicism
Frozen embryo transfer
Oocyte donation
Placenta immunology
Placental biomarkers
Placental metabolism
Placental vascularization

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10.1007/978-3-030-84725-8_33

Cite this

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abstract = "Since the birth of Louise Brown, the first “test tube baby, {"} in 1978, assisted reproductive technology (ART) has been widely implemented as a standard treatment for couples with subfertility problems. An estimated 8 million children have been born via ART worldwide and up to 6% of newborns in Europe and 1.5% in United States are conceived via this technique [2]. ART pregnancies are at an increased risk for neonatal complications such as preterm birth and low birth weight as well as maternal complications such as gestational diabetes and preeclampsia. The exact mechanism behind the adverse outcomes is not known, but a role for the placenta is likely. In this chapter we will summarize current knowledge on human placenta development and functioning in relation to ART treatments. We will focus on morphology, vascularization, immunology, placental biomarkers, and aneuploidies.",

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author = "Cantineau, {Astrid E.P.} and Vrouwenraets, {Cato J.} and {van Montfoort}, {Aafke P.A.}",

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Assisted Reproductive Technologies. / Cantineau, Astrid E.P.; Vrouwenraets, Cato J.; van Montfoort, Aafke P.A.
Benirschke’s Pathology of the Human Placenta: Seventh Edition. ed. / Rebecca N. Baergen; Graham J. Burton; Cynthia G. Kaplan. 7. ed. Springer International Publishing, 2021. p. 887-900.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic

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T1 - Assisted Reproductive Technologies

AU - Cantineau, Astrid E.P.

AU - Vrouwenraets, Cato J.

AU - van Montfoort, Aafke P.A.

N1 - Publisher Copyright: © Springer Nature Switzerland AG 2012, 2022.

PY - 2021/1/1

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AB - Since the birth of Louise Brown, the first “test tube baby, " in 1978, assisted reproductive technology (ART) has been widely implemented as a standard treatment for couples with subfertility problems. An estimated 8 million children have been born via ART worldwide and up to 6% of newborns in Europe and 1.5% in United States are conceived via this technique [2]. ART pregnancies are at an increased risk for neonatal complications such as preterm birth and low birth weight as well as maternal complications such as gestational diabetes and preeclampsia. The exact mechanism behind the adverse outcomes is not known, but a role for the placenta is likely. In this chapter we will summarize current knowledge on human placenta development and functioning in relation to ART treatments. We will focus on morphology, vascularization, immunology, placental biomarkers, and aneuploidies.

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KW - Confined placental mosaicism

KW - Frozen embryo transfer

KW - Oocyte donation

KW - Placenta immunology

KW - Placental biomarkers

KW - Placental metabolism

KW - Placental vascularization

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BT - Benirschke’s Pathology of the Human Placenta: Seventh Edition

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A2 - Kaplan, Cynthia G.

PB - Springer International Publishing

ER -

Assisted Reproductive Technologies

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Keywords

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