Assessment of Health-Related Quality of Life after TBI: Comparison of a Disease-Specific (QOLIBRI) with a Generic (SF-36) Instrument

N. von Steinbuechel*, A. Covic, S. Polinder, T. Kohlmann, U Cepulyte, H Poinstingl, Joy Backhaus, W. Bakx, A. Christensen, R. Formisano, H. Gibbons, S. Höfer, S. Koskinen, A. Maas, E. Neugebauer, J Powell, J Sarajuuri, N Sasse, S. Schmidt, E MühlanK von Wild, G. Zitnay, J.L. Truelle

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Psychosocial, emotional, and physical problems can emerge after traumatic brain injury (TBI), potentially impacting health-related quality of life (HRQoL). Until now, however, neither the discriminatory power of disease-specific (QOLIBRI) and generic (SF-36) HRQoL nor their correlates have been compared in detail. These aspects as well as some psychometric item characteristics were studied in a sample of 795 TBI survivors. The Shannon H' index absolute informativity, as an indicator of an instrument's power to differentiate between individuals within a specific group or health state, was investigated. Psychometric performance of the two instruments was predominantly good, generally higher, and more homogenous for the QOLIBRI than for the SF-36 subscales. Notably, the SF-36 "Role Physical," " Role Emotional," and "Social Functioning" subscales showed less satisfactory discriminatory power than all other dimensions or the sum scores of both instruments. The absolute informativity of disease-specific as well as generic HRQoL instruments concerning the different groups defined by different correlates differed significantly. When the focus is on how a certain subscale or sum score differentiates between individuals in one specific dimension/health state, the QOLIBRI can be recommended as the preferable instrument.

Original languageEnglish
Article number7928014
Number of pages14
JournalBehavioural Neurology
Publication statusPublished - 1 Jan 2016


  • 1ST YEAR
  • MILD
  • EQ-5D

Cite this