Abstract
To the Editor: Aspirin for thromboprophylaxis to prevent venous thromboembolism after hip- or knee-replacement surgery has been included in clinical guidelines. Although the use of aspirin thromboprophylaxis for venous thromboembolism in hip and knee replacements is still in debate, data on its use in patients with extremity fracture (in the hip to midfoot or shoulder to wrist) are limited.(1) In the Prevention of Clot in Orthopaedic Trauma (PREVENT CLOT) trial, the Major Extremity Trauma Research Consortium (METRC) investigators (Jan. 19 issue)(2) tested the noninferiority of aspirin as compared with low-molecular-weight heparin for thromboprophylaxis in patients after an extremity fracture treated . . .
| Original language | English |
|---|---|
| Article number | e57 |
| Number of pages | 1 |
| Journal | New England Journal of Medicine |
| Volume | 388 |
| Issue number | 16 |
| DOIs | |
| Publication status | Published - 20 Apr 2023 |
Keywords
- Humans
- Aspirin/adverse effects
- Heparin, Low-Molecular-Weight/therapeutic use
- Anticoagulants/adverse effects
- Venous Thromboembolism/prevention & control
- Pulmonary Embolism/prevention & control
- Fractures, Bone/prevention & control