Application of stem cells in orthopedics

Andreas Schmitt*, Martijn van Griensven, Andreas B Imhoff, Stefan Buchmann

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Stem cell research plays an important role in orthopedic regenerative medicine today. Current literature provides us with promising results from animal research in the fields of bone, tendon, and cartilage repair. While early clinical results are already published for bone and cartilage repair, the data about tendon repair is limited to animal studies. The success of these techniques remains inconsistent in all three mentioned areas. This may be due to different application techniques varying from simple mesenchymal stem cell injection up to complex tissue engineering. However, the ideal carrier for the stem cells still remains controversial. This paper aims to provide a better understanding of current basic research and clinical data concerning stem cell research in bone, tendon, and cartilage repair. Furthermore, a focus is set on different stem cell application techniques in tendon reconstruction, cartilage repair, and filling of bone defects.

Original languageEnglish
Article number394962
JournalStem Cells International
Volume2012
DOIs
Publication statusPublished - 2012
Externally publishedYes

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