Annexin A1 and annexin A5 in cardiovascular disease

D.H.M. Kusters

Research output: ThesisDoctoral ThesisInternal

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Abstract

This study involves two members of the annexin family of proteins and their relationship to cardiovascular disease. The main findings are the inhibiting effect of annexin A5 on clearing away dead cells and, therefore, the enhancing effect on ‘arteriosclerosis’. Annexin A1 has an anti-inflammatory effect and was successful in the treatment of ‘arteriosclerosis’ as well as the reduction of damage following myocardial infarction. These findings may lead to the development of new drugs.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Maastricht University
Supervisors/Advisors
  • Reutelingsperger, Christiaan, Supervisor
  • Schürgers, L.J., Advisor, External person
Award date6 Feb 2015
Place of PublicationMaastricht
Publisher
Print ISBNs9789462950801
Publication statusPublished - 2015

Keywords

  • cardiovascular disease
  • proteins
  • arteriosclerosis

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