Aneuploidy in human preimplantation embryos

Joseph P.M. Geraedts

doi:10.1007/978-3-319-14874-8_17

Aneuploidy in human preimplantation embryos

Joseph P.M. Geraedts^*

^*Corresponding author for this work

GROW - Reproductive and Perinatal Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic

Abstract

Even when conditions are optimal, the chance of a clinically recognized pregnancy occurring in a given menstrual cycle is much less than half. Besides failure of conception pre-clinical pregnancy loss is a major cause for the low fecundity observed in humans. Chromosome abnormalities are the predominant cause of this clinical problem, both in natural conceptions as well as after assisted reproduction [21]. About 42 % of all oocytes exposed to natural fertilization survive until after implantation, and only 31 % will lead to a live birth (Fig. 17.1).

Original language	English
Title of host publication	Human Fetal Growth and Development: First and Second Trimesters
Editors	Niranjan Bhattacharya, Philip G. Stubblefield
Publisher	Springer International Publishing
Pages	231-236
Number of pages	6
ISBN (Electronic)	9783319148748
ISBN (Print)	9783319148731
DOIs	https://doi.org/10.1007/978-3-319-14874-8_17
Publication status	Published - 2016

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10.1007/978-3-319-14874-8_17

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AB - Even when conditions are optimal, the chance of a clinically recognized pregnancy occurring in a given menstrual cycle is much less than half. Besides failure of conception pre-clinical pregnancy loss is a major cause for the low fecundity observed in humans. Chromosome abnormalities are the predominant cause of this clinical problem, both in natural conceptions as well as after assisted reproduction [21]. About 42 % of all oocytes exposed to natural fertilization survive until after implantation, and only 31 % will lead to a live birth (Fig. 17.1).

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M3 - Chapter

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ER -

Aneuploidy in human preimplantation embryos

Abstract

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