An overview in acquired hemophilia A: a rare but complicated disease

Samantha Pasca

Research output: ThesisDoctoral ThesisExternal prepared

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Abstract

This thesis focused on acquired hemophilia A, a rare coagulation disorder that equally affects males and females. However, there are two different peaks of incidence: in older age and, in the case of young women, during pregnancy/puerperium. This thesis analyzed, in particular, diagnostic difficulties and the main treatments currently available to clinicians, highlighting their pros and cons. Flow charts were designed to allow clinicians, who find themselves having to manage patients with acquired hemophilia A, to follow well-defined and clear diagnostic-therapeutic pathways. This thesis also discussed the cost of treatment and the need to establish training courses for clinicians and laboratory medicine experts to suspect hemophilia A in the shortest time possible.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Maastricht University
Supervisors/Advisors
  • ten Cate, Hugo, Supervisor
  • Mannuccio, Pier, Supervisor, External person
  • Zanon, E., Co-Supervisor, External person
Award date9 Oct 2023
Place of PublicationMaastricht
Publisher
DOIs
Publication statusPublished - 2023

Keywords

  • Acquired hemophilia A
  • Rare bleeding disorders
  • Coagulation

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