Ampullary carcinoid and neurofibromatosis: case report and review of the literature

J.P. van Basten, B. van Hoek, A.P. de Bruine, J.W. Arends, R.W. Stockbrügger

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Abstract

Ampullary carcinoid and neurofibromatosis: case report and review of the literature.

van Basten JP, van Hoek B, de Bruine A, Arends JW, Stockbrugger RW.

Department of Internal Medicine, University Hospital, Maastricht, Netherlands.

A 49-year-old woman is reported with an ampullary carcinoid and von Recklinghausen's neurofibromatosis, presenting with melaena. On upper GI-endoscopy a tumour of the ampulla of Vater was seen. Histochemical examination revealed a carcinoid tumour. A review of the literature shows that patients with von Recklinghausen's neurofibromatosis are at increased risk for developing tumours of neuroectodermal origin, with the ampulla of Vater as predilection site. Therefore, early diagnostic evaluation, primarily by gastroduodenoscopy, for malignancies in patients with von Recklinghausen's neurofibromatosis and abdominal discomfort is recommended. Surgical removal is the only therapy so far evaluated
Original languageEnglish
Pages (from-to)202-206
JournalNetherlands Journal of Medicine
Volume44
Issue number6
Publication statusPublished - 1 Jan 1994

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