Additional evidence for the existence of a precursor molecule of the prothrombin complex in oral anticoagulation

J.J. Veltkamp; H. Muis; A.D. Muller; H.C. Hemker; E.A. Loeliger

doi:10.1055/S-0038-1654305

Additional evidence for the existence of a precursor molecule of the prothrombin complex in oral anticoagulation

J.J. Veltkamp, H. Muis, A.D. Muller, H.C. Hemker, E.A. Loeliger

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Abstract

By means of the PTC-inhibitor neutralizing test (12) a significant excess of PTC (factor IX)-like material over factor IX activity could be demonstrated in human coumarin plasma. This cross-reacting material is considered to be a precursor of one or all of the clotting factors of the prothrombin complex.

Original language	English
Pages (from-to)	312-315
Number of pages	4
Journal	Thrombosis et diathesis haemorrhagica
Volume	25
Issue number	2
DOIs	https://doi.org/10.1055/S-0038-1654305
Publication status	Published - 30 Jun 1971

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title = "Additional evidence for the existence of a precursor molecule of the prothrombin complex in oral anticoagulation",

abstract = "By means of the PTC-inhibitor neutralizing test (12) a significant excess of PTC (factor IX)-like material over factor IX activity could be demonstrated in human coumarin plasma. This cross-reacting material is considered to be a precursor of one or all of the clotting factors of the prothrombin complex.",

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AU - Muis, H.

AU - Muller, A.D.

AU - Hemker, H.C.

AU - Loeliger, E.A.

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AB - By means of the PTC-inhibitor neutralizing test (12) a significant excess of PTC (factor IX)-like material over factor IX activity could be demonstrated in human coumarin plasma. This cross-reacting material is considered to be a precursor of one or all of the clotting factors of the prothrombin complex.

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DO - 10.1055/S-0038-1654305

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