Additional evidence for the existence of a precursor molecule of the prothrombin complex in oral anticoagulation

J.J. Veltkamp, H. Muis, A.D. Muller, H.C. Hemker, E.A. Loeliger

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    By means of the PTC-inhibitor neutralizing test (12) a significant excess of PTC (factor IX)-like material over factor IX activity could be demonstrated in human coumarin plasma. This cross-reacting material is considered to be a precursor of one or all of the clotting factors of the prothrombin complex.
    Original languageEnglish
    Pages (from-to)312-315
    Number of pages4
    JournalThrombosis et diathesis haemorrhagica
    Issue number2
    Publication statusPublished - 30 Jun 1971

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