Activation of the NLRP3 inflammasome in microglia: the role of ceramide

Hannah Scheiblich, Anna Schlütter, Douglas T. Golenbock, Eicke Latz, Pilar Martinez-Martinez, Michael T. Heneka*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)534-550
Number of pages17
JournalJournal of Neurochemistry
Volume143
Issue number5
DOIs
Publication statusPublished - Dec 2017

Keywords

  • ASC
  • Caspase-1
  • ceramide
  • IL-1 beta
  • microglia
  • NLRP3 inflammasome
  • INTERLEUKIN-1 RECEPTOR ANTAGONIST
  • ALZHEIMERS-DISEASE
  • SERINE PALMITOYLTRANSFERASE
  • AMYLOID-BETA
  • PATTERN-RECOGNITION
  • INDUCED APOPTOSIS
  • PRIMARY NEURONS
  • POTENTIAL ROLE
  • FATTY-ACIDS
  • CELL-DEATH

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