Activation of 5-HT1A postsynaptic receptors by NLX-101 results in functional recovery and an increase in neuroplasticity in mice with brain ischemia

Rafael Pazinatto Aguiar, Ligia Mendes Soares, Erika Meyer, Fernanda Canova da Silveira, Humberto Milani, Adrian Newman-Tancredi, Mark Varney, Jos Prickaerts, Rubia M. Weffort Oliveira*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number109832
Number of pages12
JournalProgress in Neuro-Psychopharmacology & Biological Psychiatry
Volume99
DOIs
Publication statusPublished - 20 Apr 2020

Keywords

  • NLX-101
  • 5-HT1A receptor
  • Brain ischemia
  • Neuroprotection
  • GLOBAL CEREBRAL-ISCHEMIA
  • TRANSIENT FOREBRAIN ISCHEMIA
  • NEUROPROTECTIVE MELATONIN TREATMENT
  • CHRONICALLY STRESSED MICE
  • HIPPOCAMPAL CA1 REGION
  • LONG-TERM
  • PYRAMIDAL NEURONS
  • SPINE DENSITY
  • RAT-BRAIN
  • SYNAPTOPHYSIN EXPRESSION

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