A Thermal Sublimation Generator of 131mXe

K. Kulesz; Nikolay Azaryan; M. Baranowski; Mateusz Jerzy Chojnacki; U. Koster; Razvan Lica; Sorin Gabriel Pascu; Renaud Jolivet; M. Kowalska

doi:10.3390/instruments6040076

A Thermal Sublimation Generator of 131mXe

K. Kulesz, Nikolay Azaryan, M. Baranowski, Mateusz Jerzy Chojnacki, U. Koster, Razvan Lica, Sorin Gabriel Pascu, Renaud Jolivet^*, M. Kowalska^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Stable and unstable isotopes of the heavy noble gas xenon find use in various medical applications. However, apart from 133 Xe, used for Single Photon Emission Computed Tomography, radioactive isotopes of xenon are currently complicated to obtain in small quantities. With the GAMMA-MRI project in mind, we investigated a thermal sublimation generator of the long-lived excited state (isomer) 131 m Xe. This production method utilized the decay of 131 I, obtained commercially from a hospital supplier in the form of Na 131 I powder. Heat treatments of the Na 131 I powder and cryogenic trapping of released 131 m Xe allowed us to collect up to 88% of the produced xenon. Our method provides an isomeric mixture of 131 m Xe and 131 Xe. With improvements in scalability and chemical purification, this method could be a cost-effective source of 131 m Xe for small-scale experiments.

Original language	English
Pages (from-to)	76
Journal	Instruments
Volume	6
DOIs	https://doi.org/10.3390/instruments6040076
Publication status	Published - 16 Nov 2022

Access to Document

10.3390/instruments6040076

Cite this

@article{ab7857b3027947349c8392e36205910d,

title = "A Thermal Sublimation Generator of 131mXe",

abstract = "Stable and unstable isotopes of the heavy noble gas xenon find use in various medical applications. However, apart from 133 Xe, used for Single Photon Emission Computed Tomography, radioactive isotopes of xenon are currently complicated to obtain in small quantities. With the GAMMA-MRI project in mind, we investigated a thermal sublimation generator of the long-lived excited state (isomer) 131 m Xe. This production method utilized the decay of 131 I, obtained commercially from a hospital supplier in the form of Na 131 I powder. Heat treatments of the Na 131 I powder and cryogenic trapping of released 131 m Xe allowed us to collect up to 88% of the produced xenon. Our method provides an isomeric mixture of 131 m Xe and 131 Xe. With improvements in scalability and chemical purification, this method could be a cost-effective source of 131 m Xe for small-scale experiments.",

author = "K. Kulesz and Nikolay Azaryan and M. Baranowski and Chojnacki, {Mateusz Jerzy} and U. Koster and Razvan Lica and Pascu, {Sorin Gabriel} and Renaud Jolivet and M. Kowalska",

year = "2022",

month = nov,

day = "16",

doi = "10.3390/instruments6040076",

language = "English",

volume = "6",

pages = "76",

journal = "Instruments",

issn = "2410-390X",

publisher = "MDPI",

}

TY - JOUR

T1 - A Thermal Sublimation Generator of 131mXe

AU - Kulesz, K.

AU - Azaryan, Nikolay

AU - Baranowski, M.

AU - Chojnacki, Mateusz Jerzy

AU - Koster, U.

AU - Lica, Razvan

AU - Pascu, Sorin Gabriel

AU - Jolivet, Renaud

AU - Kowalska, M.

PY - 2022/11/16

Y1 - 2022/11/16

N2 - Stable and unstable isotopes of the heavy noble gas xenon find use in various medical applications. However, apart from 133 Xe, used for Single Photon Emission Computed Tomography, radioactive isotopes of xenon are currently complicated to obtain in small quantities. With the GAMMA-MRI project in mind, we investigated a thermal sublimation generator of the long-lived excited state (isomer) 131 m Xe. This production method utilized the decay of 131 I, obtained commercially from a hospital supplier in the form of Na 131 I powder. Heat treatments of the Na 131 I powder and cryogenic trapping of released 131 m Xe allowed us to collect up to 88% of the produced xenon. Our method provides an isomeric mixture of 131 m Xe and 131 Xe. With improvements in scalability and chemical purification, this method could be a cost-effective source of 131 m Xe for small-scale experiments.

AB - Stable and unstable isotopes of the heavy noble gas xenon find use in various medical applications. However, apart from 133 Xe, used for Single Photon Emission Computed Tomography, radioactive isotopes of xenon are currently complicated to obtain in small quantities. With the GAMMA-MRI project in mind, we investigated a thermal sublimation generator of the long-lived excited state (isomer) 131 m Xe. This production method utilized the decay of 131 I, obtained commercially from a hospital supplier in the form of Na 131 I powder. Heat treatments of the Na 131 I powder and cryogenic trapping of released 131 m Xe allowed us to collect up to 88% of the produced xenon. Our method provides an isomeric mixture of 131 m Xe and 131 Xe. With improvements in scalability and chemical purification, this method could be a cost-effective source of 131 m Xe for small-scale experiments.

U2 - 10.3390/instruments6040076

DO - 10.3390/instruments6040076

M3 - Article

SN - 2410-390X

VL - 6

SP - 76

JO - Instruments

JF - Instruments

ER -