TY - JOUR
T1 - A Thermal Sublimation Generator of 131mXe
AU - Kulesz, K.
AU - Azaryan, Nikolay
AU - Baranowski, M.
AU - Chojnacki, Mateusz Jerzy
AU - Koster, U.
AU - Lica, Razvan
AU - Pascu, Sorin Gabriel
AU - Jolivet, Renaud
AU - Kowalska, M.
N1 - Funding Information:
The GAMMA-MRI project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 964644 (GAMMA-MRI). The authors also wish to acknowledge support via the Swiss Excellence Government Scholarship, the CERN Medical Application Fund (GAMMA-MRI), and the Romanian IFA grant CERN/ISOLDE.
Publisher Copyright:
© 2022 by the authors.
PY - 2022/11/16
Y1 - 2022/11/16
N2 - Stable and unstable isotopes of the heavy noble gas xenon find use in various medical applications. However, apart from (Formula presented.) Xe, used for Single Photon Emission Computed Tomography, radioactive isotopes of xenon are currently complicated to obtain in small quantities. With the GAMMA-MRI project in mind, we investigated a thermal sublimation generator of the long-lived excited state (isomer) (Formula presented.) Xe. This production method utilized the decay of (Formula presented.) I, obtained commercially from a hospital supplier in the form of Na (Formula presented.) I powder. Heat treatments of the Na (Formula presented.) I powder and cryogenic trapping of released (Formula presented.) Xe allowed us to collect up to 88% of the produced xenon. Our method provides an isomeric mixture of (Formula presented.) Xe and (Formula presented.) Xe. With improvements in scalability and chemical purification, this method could be a cost-effective source of (Formula presented.) Xe for small-scale experiments.
AB - Stable and unstable isotopes of the heavy noble gas xenon find use in various medical applications. However, apart from (Formula presented.) Xe, used for Single Photon Emission Computed Tomography, radioactive isotopes of xenon are currently complicated to obtain in small quantities. With the GAMMA-MRI project in mind, we investigated a thermal sublimation generator of the long-lived excited state (isomer) (Formula presented.) Xe. This production method utilized the decay of (Formula presented.) I, obtained commercially from a hospital supplier in the form of Na (Formula presented.) I powder. Heat treatments of the Na (Formula presented.) I powder and cryogenic trapping of released (Formula presented.) Xe allowed us to collect up to 88% of the produced xenon. Our method provides an isomeric mixture of (Formula presented.) Xe and (Formula presented.) Xe. With improvements in scalability and chemical purification, this method could be a cost-effective source of (Formula presented.) Xe for small-scale experiments.
U2 - 10.3390/instruments6040076
DO - 10.3390/instruments6040076
M3 - Article
SN - 2410-390X
VL - 6
SP - 76
JO - Instruments
JF - Instruments
IS - 4
ER -