A new method to evaluate the effects of shear on the skin

L.A. de Wert, D.L. Bader, C.W. Oomens, L. Schoonhoven, M. Poeze, N.D. Bouvy

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Currently, pressure ulcer preventive strategies focus mainly on pressure redistribution. Little attention is paid to reduce the harmful effects of shear-force, because little is known about pathophysiological aspects of shear-force. Even today, no method to measure the effects of shear-force on the skin is available. Therefore, the aim of this study was to investigate the response to shear-forces in terms of analyzing a noninvasive biomarker and reactive hyperemic parameter measured at the skin of healthy participants. A physical model was developed to produce a combination of pressure and shear or pressure alone on the skin. Ten healthy male participants were included and pressure (3.9 kPa) and a combined loading of pressure and shear (2.4 kPa + 14.5 N) was applied at the volar aspect of the forearms for 15 and 30 minutes. A Sebutape sample was used to collect IL-1alpha and total protein (TP) noninvasively. The reactive hyperemic parameter was derived from a laser Doppler flowmeter. The increase in IL-1alpha/TP-ratio after a combined loading of pressure and shear for 30 minutes of 6.2 +/- 2.5 was significantly higher compared with all other test conditions (p < 0.05). The increase in cutaneous blood cell flux was already significantly higher when a combined loading of pressure and shear was applied for 15 minutes compared with pressure alone. These results shows that the IL-1alpha/TP-ratio and cutaneous blood cell flux can be used as robust measures of the effect of shear-force on skin in humans. Therefore, this model can be used to evaluate materials aimed at the reduction of shear.
Original languageEnglish
Pages (from-to)885-890
Number of pages6
JournalWound Repair and Regeneration
Volume23
Issue number6
DOIs
Publication statusPublished - 1 Jan 2015

Keywords

  • BLOOD-FLOW
  • PRESSURE ULCERS
  • DECUBITUS ULCERS
  • TISSUE
  • ERYTHEMA
  • FORCE
  • TEMPERATURE
  • POSITIONS
  • RELEASE
  • LOADS

Cite this

de Wert, L. A., Bader, D. L., Oomens, C. W., Schoonhoven, L., Poeze, M., & Bouvy, N. D. (2015). A new method to evaluate the effects of shear on the skin. Wound Repair and Regeneration, 23(6), 885-890. https://doi.org/10.1111/wrr.12368