spillR

  • Marco Guazzini (Contributor)
  • Alexander Reisach (Contributor)
  • Sebastian Weichwald (Creator)
  • Christof Seiler (Contributor)

Dataset

Description

Channel interference in mass cytometry can cause spillover and may result in miscounting of protein markers. We develop a nonparametric finite mixture model, and use the mixture components to estimate the probability of spillover. We implement our method using expectation-maximization to fit the mixture model.
Date made available2023
PublisherBioconductor

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