%PDF-1.7
%
1 0 obj
<<
/PageMode /UseOutlines
/Names 2 0 R
/Outlines 3 0 R
/Metadata 4 0 R
/Pages 5 0 R
/PageLayout /SinglePage
/OpenAction [6 0 R /FitH 810]
/Threads [7 0 R]
/StructTreeRoot 8 0 R
/Type /Catalog
/PageLabels 9 0 R
>>
endobj
10 0 obj
<<
/CrossMarkDomains#5B2#5D (elsevier.com)
/CrossmarkMajorVersionDate (2010-04-23)
/CreationDate (20th October 2015)
/Subject (Journal of Clinical Epidemiology, 68 \(2015\) 1375-1379. doi:10.1016/j.jclinepi.2015.04.014)
/Author (Wolfgang Viechtbauer)
/CreationDate--Text (20th October 2015)
/Creator (Elsevier)
/Producer (Acrobat Distiller 8.1.0 \(Windows\))
/ElsevierWebPDFSpecifications (6.4)
/CrossmarkDomainExclusive (true)
/robots (noindex)
/ModDate (D:20151021013038+05'30')
/doi (10.1016/j.jclinepi.2015.04.014)
/CrossMarkDomains#5B1#5D (sciencedirect.com)
/Title (A simple formula for the calculation of sample size in pilot studies)
>>
endobj
2 0 obj
<<
/Dests 11 0 R
>>
endobj
3 0 obj
<<
/First 12 0 R
/Count 6
/Last 12 0 R
>>
endobj
4 0 obj
<<
/Length 7199
/Subtype /XML
/Type /Metadata
>>
stream
application/pdf
doi:10.1016/j.jclinepi.2015.04.014
A simple formula for the calculation of sample size in pilot studies
Wolfgang Viechtbauer
Luc Smits
Daniel Kotz
Luc Budé
Mark Spigt
Jan Serroyen
Rik Crutzen
Pilot study
Sample size
Problem detection
Rule of three
Unforeseen problems
Journal of Clinical Epidemiology, 68 (2015) 1375-1379. doi:10.1016/j.jclinepi.2015.04.014
Elsevier Inc
journal
Journal of Clinical Epidemiology
Copyright © 2015 Elsevier Inc. All rights reserved.
0895-4356
68
11
November 2015
201511
1375-1379
1375
1379
10.1016/j.jclinepi.2015.04.014
http://dx.doi.org/10.1016/j.jclinepi.2015.04.014
2010-04-23
true
10.1016/j.jclinepi.2015.04.014
elsevier.com
sciencedirect.com
0e0a7e43-6038-4d26-af84-f1f3b9875f4f:1559809124
10.1016/j.jclinepi.2015.04.014
noindex
2010-04-23
true
20th October 2015
sciencedirect.com
elsevier.com
Elsevier
2015-10-21T01:30:38+05:30
2015-10-21T01:30:38+05:30
True
20th October 2015
Acrobat Distiller 8.1.0 (Windows)
uuid:affb673d-b36a-416f-947a-bca8f546f9b4
uuid:99255d9f-6dcb-4e7e-843c-663b469f16c1
endstream
endobj
5 0 obj
<<
/Count 6
/Type /Pages
/Kids [13 0 R 6 0 R 14 0 R 15 0 R 16 0 R 17 0 R]
>>
endobj
6 0 obj
<<
/CropBox [0 0 593.972 792]
/Annots [18 0 R 19 0 R 20 0 R 21 0 R 22 0 R 23 0 R 24 0 R 25 0 R 26 0 R 27 0 R
28 0 R 29 0 R 30 0 R 31 0 R 32 0 R 33 0 R 34 0 R 35 0 R 36 0 R 37 0 R
38 0 R 39 0 R 40 0 R 41 0 R]
/Parent 5 0 R
/B [42 0 R 43 0 R 44 0 R 45 0 R 46 0 R 47 0 R 48 0 R 49 0 R]
/StructParents 1
/Contents [50 0 R 51 0 R 52 0 R 53 0 R 54 0 R 55 0 R 56 0 R 57 0 R]
/Rotate 0
/MediaBox [0 0 593.972 792]
/Resources 58 0 R
/Type /Page
>>
endobj
7 0 obj
<<
/F 42 0 R
/I 59 0 R
>>
endobj
8 0 obj
<<
/K [60 0 R 61 0 R 62 0 R]
/ParentTree 63 0 R
/ParentTreeNextKey 3
/Type /StructTreeRoot
>>
endobj
9 0 obj
<<
/Nums [0 64 0 R]
>>
endobj
11 0 obj
<<
/Kids [65 0 R]
>>
endobj
12 0 obj
<<
/First 66 0 R
/Parent 3 0 R
/Dest
/Count 5
/Last 67 0 R
/Title
>>
endobj
13 0 obj
<<
/Contents 68 0 R
/Type /Page
/Resources <<
/Font <<
/F1 69 0 R
/F2 70 0 R
/F3 71 0 R
/F4 72 0 R
>>
/XObject <<
/Xf1 73 0 R
>>
>>
/Annots [74 0 R 75 0 R 76 0 R]
/Parent 5 0 R
/MediaBox [0 0 595 842]
>>
endobj
14 0 obj
<<
/CropBox [0 0 593.972 792]
/Annots [77 0 R 78 0 R 79 0 R 80 0 R 81 0 R 82 0 R 83 0 R 84 0 R 85 0 R 86 0 R
87 0 R 88 0 R]
/Parent 5 0 R
/B [89 0 R 90 0 R 91 0 R 92 0 R 93 0 R 94 0 R 95 0 R 96 0 R]
/Contents 97 0 R
/Rotate 0
/MediaBox [0 0 593.972 792]
/Resources 98 0 R
/Type /Page
>>
endobj
15 0 obj
<<
/CropBox [0 0 593.972 792]
/Annots [99 0 R 100 0 R 101 0 R]
/Parent 5 0 R
/B [102 0 R 103 0 R]
/StructParents 2
/Contents 104 0 R
/Rotate 0
/MediaBox [0 0 593.972 792]
/Resources 105 0 R
/Type /Page
>>
endobj
16 0 obj
<<
/CropBox [0 0 593.972 792]
/Annots [106 0 R 107 0 R 108 0 R 109 0 R 110 0 R 111 0 R 112 0 R 113 0 R 114 0 R 115 0 R
116 0 R 117 0 R 118 0 R 119 0 R 120 0 R 121 0 R 122 0 R 123 0 R 124 0 R 125 0 R
126 0 R 127 0 R 128 0 R 129 0 R 130 0 R 131 0 R 132 0 R 133 0 R 134 0 R 135 0 R
136 0 R 137 0 R 138 0 R 139 0 R 140 0 R 141 0 R 142 0 R 143 0 R 144 0 R 145 0 R]
/Parent 5 0 R
/B [146 0 R 147 0 R 148 0 R 149 0 R]
/Contents 150 0 R
/Rotate 0
/MediaBox [0 0 593.972 792]
/Resources 151 0 R
/Type /Page
>>
endobj
17 0 obj
<<
/CropBox [0 0 593.972 792]
/Annots [152 0 R 153 0 R 154 0 R 155 0 R 156 0 R 157 0 R 158 0 R 159 0 R 160 0 R 161 0 R
162 0 R 163 0 R 164 0 R 165 0 R 166 0 R]
/Parent 5 0 R
/B [167 0 R 168 0 R 169 0 R]
/Contents 170 0 R
/Rotate 0
/MediaBox [0 0 593.972 792]
/Resources 171 0 R
/Type /Page
>>
endobj
18 0 obj
<<
/Rect [90.652 613.814 90.652 616.422]
/Subtype /Link
/A 172 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
19 0 obj
<<
/Rect [208.857 611.886 213.165 624.869]
/Subtype /Link
/Border [0 0 0]
/Dest
/Type /Annot
>>
endobj
20 0 obj
<<
/Rect [220.762 613.814 220.762 616.422]
/Subtype /Link
/A 173 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
21 0 obj
<<
/Rect [274.847 611.886 279.666 624.869]
/Subtype /Link
/Border [0 0 0]
/Dest
/Type /Annot
>>
endobj
22 0 obj
<<
/Rect [287.263 613.814 287.263 616.422]
/Subtype /Link
/A 174 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
23 0 obj
<<
/Rect [351.042 611.886 355.408 624.869]
/Subtype /Link
/Border [0 0 0]
/Dest
/Type /Annot
>>
endobj
24 0 obj
<<
/Rect [357.846 611.886 362.664 624.869]
/Subtype /Link
/Border [0 0 0]
/Dest
/Type /Annot
>>
endobj
25 0 obj
<<
/Rect [370.261 613.814 370.261 616.422]
/Subtype /Link
/A 175 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
26 0 obj
<<
/Rect [422.192 611.886 426.557 624.869]
/Subtype /Link
/Border [0 0 0]
/Dest
/Type /Annot
>>
endobj
27 0 obj
<<
/Rect [434.098 613.814 434.098 616.422]
/Subtype /Link
/A 176 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
28 0 obj
<<
/Rect [493.852 611.886 498.217 624.869]
/Subtype /Link
/Border [0 0 0]
/Dest
/Type /Annot
>>
endobj
29 0 obj
<<
/Rect [500.655 611.886 503.886 624.869]
/Subtype /Link
/Border [0 0 0]
/Dest
/Type /Annot
>>
endobj
30 0 obj
<<
/Rect [219.458 598.904 219.515 601.512]
/Subtype /Link
/A 177 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
31 0 obj
<<
/Rect [287.887 596.976 292.762 609.902]
/Subtype /Link
/Border [0 0 0]
/Dest
/Type /Annot
>>
endobj
32 0 obj
<<
/Rect [300.302 598.904 300.302 601.512]
/Subtype /Link
/A 178 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
33 0 obj
<<
/Rect [364.535 596.976 369.354 609.902]
/Subtype /Link
/Border [0 0 0]
/Dest
/Type /Annot
>>
endobj
34 0 obj
<<
/Rect [371.792 596.976 378.255 609.902]
/Subtype /Link
/Border [0 0 0]
/Dest
/Type /Annot
>>
endobj
35 0 obj
<<
/Rect [169.852 196.328 181.531 206.249]
/Subtype /Link
/Border [0 0 0]
/Dest
/Type /Annot
>>
endobj
36 0 obj
<<
/Rect [520.611 239.131 532.233 249.109]
/Subtype /Link
/Border [0 0 0]
/Dest
/Type /Annot
>>
endobj
37 0 obj
<<
/Rect [114.69 60.151 228.926 68.145]
/Subtype /Link
/A 179 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
38 0 obj
<<
/Rect [137.934 710.249 168.321 744.378]
/Subtype /Link
/A 180 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
39 0 obj
<<
/Rect [47.849 42.803 199.786 50.797]
/Subtype /Link
/A 181 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
40 0 obj
<<
/Rect [207.156 681.732 368.731 689.669]
/Subtype /Link
/A 182 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
41 0 obj
<<
/Rect [368.731 681.732 390.557 689.669]
/Subtype /Link
/A 183 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
42 0 obj
<<
/N 43 0 R
/P 6 0 R
/R [45 724 290 729]
/T 7 0 R
/V 169 0 R
>>
endobj
43 0 obj
<<
/N 44 0 R
/P 6 0 R
/R [45 441 553 675]
/T 7 0 R
/V 42 0 R
>>
endobj
44 0 obj
<<
/N 45 0 R
/P 6 0 R
/R [45 433 290 450]
/T 7 0 R
/V 43 0 R
>>
endobj
45 0 obj
<<
/N 46 0 R
/P 6 0 R
/R [45 411 553 429]
/T 7 0 R
/V 44 0 R
>>
endobj
46 0 obj
<<
/N 47 0 R
/P 6 0 R
/R [45 404 290 423]
/T 7 0 R
/V 45 0 R
>>
endobj
47 0 obj
<<
/N 48 0 R
/P 6 0 R
/R [45 269 553 405]
/T 7 0 R
/V 46 0 R
>>
endobj
48 0 obj
<<
/N 49 0 R
/P 6 0 R
/R [45 158 290 268]
/T 7 0 R
/V 47 0 R
>>
endobj
49 0 obj
<<
/N 89 0 R
/P 6 0 R
/R [308 57 553 268]
/T 7 0 R
/V 48 0 R
>>
endobj
50 0 obj
<<
/Length 915
/Filter /FlateDecode
>>
stream
HUn8l\REXN&h..TR I~LD f10`=96fA~'\7NV۹ +iǼDKÜpɸdƔ.fF2g$`tN \3aYPVyp*˄0]3[R W:1Gmn-ӸMv0Iˢ.h?yڮG}qq~$O^Wu;$0WUoLH0):pf
ÄpXүж^ofHߋ}F9SϬRH7+9[tʼ%L&a\ǓY~!ŏSp~ؗ)|Mj8
?$VhX:(>Xvौ`\Ky1v,`8ytIhd
IYf)>ݯ@N4 KFnjٿAKDx:q*
Y6=-FR,ί0Q/UT,eIgR 8;.yѤ)t0xw0ӠJOG AZ%Lr:j~djʌqA1d9,Pxt
sI
SB:91 Ɔ(Rns9^2 1nnLճx]t.6(Nߔ@VwH0-mnnr[_հܶm.pjBz
<
nE=lq ( z]ھbS-$Ue.9 MWj (sND+,=mZa_g 0nlh= Yxd y1@23C=.RzbM5j!-E`
endstream
endobj
51 0 obj
<<
/Length 930
/Filter /FlateDecode
>>
stream
HVK6БlDZMv`S#q/]Ht@@gҖ./"93~|3~ 7S1m|)ZS]ιMkG
Y\{Wߖ9`&ikx%u.ŕ]jb8bȣqX n Tc
g]gvx
)Uopͳ1ܤKCO\r;.wWW`b-ْS7Wd
0nCv