Abstract
Whipple's disease: a difficult diagnosis?
Peters FP, Elbrecht EA, Wouters RS, Engels LG, Stockbrugger RW.
Department of Gastroenterology, University Hospital Maastricht, Netherlands.
We present 3 patients with Whipple's disease all characterized by a longstanding prodromal period with progressive weight loss, diarrhoea, lymphadenitis and arthralgia or arthritis. Sarcoid-like Whipple's disease was diagnosed in one patient. He was treated with antibiotics. Initially his condition improved; however, a cerebral relapse developed which was treated successfully by ceftriaxone and cefixime. Extraintestinal Whipple's disease (lymph node localisation) was diagnosed in another patient treated successfully with antibiotics. A third case of Whipple's disease was unexpectedly diagnosed by laparotomy and partial small bowel resection. He was not treated till 2 years later with tetracycline. After 1 year of treatment his condition had improved.
Publication Types:
Case Reports
Review
Review, Tutorial
Peters FP, Elbrecht EA, Wouters RS, Engels LG, Stockbrugger RW.
Department of Gastroenterology, University Hospital Maastricht, Netherlands.
We present 3 patients with Whipple's disease all characterized by a longstanding prodromal period with progressive weight loss, diarrhoea, lymphadenitis and arthralgia or arthritis. Sarcoid-like Whipple's disease was diagnosed in one patient. He was treated with antibiotics. Initially his condition improved; however, a cerebral relapse developed which was treated successfully by ceftriaxone and cefixime. Extraintestinal Whipple's disease (lymph node localisation) was diagnosed in another patient treated successfully with antibiotics. A third case of Whipple's disease was unexpectedly diagnosed by laparotomy and partial small bowel resection. He was not treated till 2 years later with tetracycline. After 1 year of treatment his condition had improved.
Publication Types:
Case Reports
Review
Review, Tutorial
| Original language | English |
|---|---|
| Pages (from-to) | 106-111 |
| Journal | Netherlands Journal of Medicine |
| Volume | 49 |
| DOIs | |
| Publication status | Published - 1 Jan 1996 |