TY - JOUR
T1 - Visual Areas Exert Feedforward and Feedback Influences through Distinct Frequency Channels
AU - Bastos, Andre Moraes
AU - Vezoli, Julien
AU - Bosman, Conrado Arturo
AU - Schoffelen, Jan-Mathijs
AU - Oostenveld, Robert
AU - Dowdall, Jarrod Robert
AU - De Weerd, Peter
AU - Kennedy, Henry
AU - Fries, Pascal
PY - 2015/1/21
Y1 - 2015/1/21
N2 - Visual cortical areas subserve cognitive functions by interacting in both feedforward and feedback directions. While feedforward influences convey sensory signals, feedback influences modulate feedforward signaling according to the current behavioral context. We investigated whether these interareal influences are subserved differentially by rhythmic synchronization. We correlated frequency-specific directed influences among 28 pairs of visual areas with anatomical metrics of the feedforward or feedback character of the respective interareal projections. This revealed that in the primate visual system, feedforward influences are carried by theta-band (similar to 4 Hz) and gamma-band (similar to 60-80 Hz) synchronization, and feedback influences by beta-band (similar to 14-18 Hz) synchronization. The functional directed influences constrain a functional hierarchy similar to the anatomical hierarchy, but exhibiting task-dependent dynamic changes in particular with regard to the hierarchical positions of frontal areas. Our results demonstrate that feedforward and feedback signaling use distinct frequency channels, suggesting that they subserve differential communication requirements.
AB - Visual cortical areas subserve cognitive functions by interacting in both feedforward and feedback directions. While feedforward influences convey sensory signals, feedback influences modulate feedforward signaling according to the current behavioral context. We investigated whether these interareal influences are subserved differentially by rhythmic synchronization. We correlated frequency-specific directed influences among 28 pairs of visual areas with anatomical metrics of the feedforward or feedback character of the respective interareal projections. This revealed that in the primate visual system, feedforward influences are carried by theta-band (similar to 4 Hz) and gamma-band (similar to 60-80 Hz) synchronization, and feedback influences by beta-band (similar to 14-18 Hz) synchronization. The functional directed influences constrain a functional hierarchy similar to the anatomical hierarchy, but exhibiting task-dependent dynamic changes in particular with regard to the hierarchical positions of frontal areas. Our results demonstrate that feedforward and feedback signaling use distinct frequency channels, suggesting that they subserve differential communication requirements.
U2 - 10.1016/j.neuron.2014.12.018
DO - 10.1016/j.neuron.2014.12.018
M3 - Article
SN - 0896-6273
VL - 85
SP - 390
EP - 401
JO - Neuron
JF - Neuron
IS - 2
ER -