Validation, optimisation, and application data in support of the development of a targeted selected ion monitoring assay for degraded cardiac troponin T

Alexander Streng; Douwe de Boer; Freek Bouwman; Edwin Mariman; A. Scholten; Marja P. van Dieijen - Visser; Will Wodzig

doi:10.1016/j.dib.2016.02.051

Validation, optimisation, and application data in support of the development of a targeted selected ion monitoring assay for degraded cardiac troponin T

Alexander Streng, Douwe de Boer, Freek Bouwman, Edwin Mariman, A. Scholten, Marja P. van Dieijen - Visser, Will Wodzig^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Cardiac troponin T (cTnT) fragmentation in human serum was investigated using a newly developed targeted selected ion monitoring assay, as described in the accompanying article: "Development of a targeted selected ion monitoring assay for the elucidation of protease induced structural changes in cardiac troponin T" W. This article presents data describing aspects of the validation and optimisation of this assay. The data consists of several figures, an excel file containing the results of a sequence identity search, and a description of the raw mass spectrometry (MS) data files, deposited in the ProteomeXchange repository with id PRIDE: PXD003187. (C) 2015 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/40).

Original language	English
Pages (from-to)	397-405
Number of pages	9
Journal	Data in brief
Volume	7
DOIs	https://doi.org/10.1016/j.dib.2016.02.051
Publication status	Published - Jun 2016

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10.1016/j.dib.2016.02.051Licence: CC BY

Cite this

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title = "Validation, optimisation, and application data in support of the development of a targeted selected ion monitoring assay for degraded cardiac troponin T",

abstract = "Cardiac troponin T (cTnT) fragmentation in human serum was investigated using a newly developed targeted selected ion monitoring assay, as described in the accompanying article: {"}Development of a targeted selected ion monitoring assay for the elucidation of protease induced structural changes in cardiac troponin T{"} W. This article presents data describing aspects of the validation and optimisation of this assay. The data consists of several figures, an excel file containing the results of a sequence identity search, and a description of the raw mass spectrometry (MS) data files, deposited in the ProteomeXchange repository with id PRIDE: PXD003187. (C) 2015 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/40).",

author = "Alexander Streng and {de Boer}, Douwe and Freek Bouwman and Edwin Mariman and A. Scholten and {van Dieijen - Visser}, {Marja P.} and Will Wodzig",

year = "2016",

month = jun,

doi = "10.1016/j.dib.2016.02.051",

language = "English",

volume = "7",

pages = "397--405",

journal = "Data in brief",

issn = "2352-3409",

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T1 - Validation, optimisation, and application data in support of the development of a targeted selected ion monitoring assay for degraded cardiac troponin T

AU - Streng, Alexander

AU - de Boer, Douwe

AU - Bouwman, Freek

AU - Mariman, Edwin

AU - Scholten, A.

AU - van Dieijen - Visser, Marja P.

AU - Wodzig, Will

PY - 2016/6

Y1 - 2016/6

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AB - Cardiac troponin T (cTnT) fragmentation in human serum was investigated using a newly developed targeted selected ion monitoring assay, as described in the accompanying article: "Development of a targeted selected ion monitoring assay for the elucidation of protease induced structural changes in cardiac troponin T" W. This article presents data describing aspects of the validation and optimisation of this assay. The data consists of several figures, an excel file containing the results of a sequence identity search, and a description of the raw mass spectrometry (MS) data files, deposited in the ProteomeXchange repository with id PRIDE: PXD003187. (C) 2015 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/40).

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DO - 10.1016/j.dib.2016.02.051

M3 - Article

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SN - 2352-3409

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