VALIDATION OF THE KING'S SARCOIDOSIS QUESTIONNAIRE (KSQ) IN A DUTCH SARCOIDOSIS POPULATION

Mirjam J. G. van Manen; Monique Wapenaar; Bert Strookappe; Marjolein Drent; Marjon Elfferich; Jolanda de Vries; Harry R. Gosker; Surinder S. Birring; Amit S. Patel; Leon van den Toorn; Bernt van den Blink; Karin Boomars; Elske Hoitsma; Marlies S. Wijsenbeek

VALIDATION OF THE KING'S SARCOIDOSIS QUESTIONNAIRE (KSQ) IN A DUTCH SARCOIDOSIS POPULATION

Mirjam J. G. van Manen, Monique Wapenaar, Bert Strookappe, Marjolein Drent, Marjon Elfferich, Jolanda de Vries, Harry R. Gosker, Surinder S. Birring, Amit S. Patel, Leon van den Toorn, Bernt van den Blink, Karin Boomars, Elske Hoitsma, Marlies S. Wijsenbeek^*

^*Corresponding author for this work

Pulmonologie

Research output: Contribution to journal › Article › Academic › peer-review

27 Downloads (Pure)

Abstract

Background: The King's Sarcoidosis Questionnaire (KSQ) is a brief questionnaire assessing health status using five modules (General Health Status, Lung, Medication, Skin, Eyes) in patients with sarcoidosis. The KSQ was only validated in one English sarcoidosis cohort. Objective: The aim of this study was to validate the KSQ in a Dutch sarcoidosis population. Methods: The KSQ was translated according to international guidelines and tested in interviews with patients. Consecutive outpatients completed multiple questionnaires twice, two weeks apart. Construct validity, internal consistency and repeatability were determined. Results: Of the 98 patients included 85 had lung, 22 skin and 24 eye disease. There was good construct validity of the KSQ General Health Status module against the World Health Organization Quality of Life-BREF questionnaire. The Medication module correlated weak to moderate with most questionnaires. The correlations with organ-specific questionnaires varied from strong for Eyes (r=0.75), Skin (r=-0.62) to moderate for Lung (r=-0.45 with MRC breathlessness scale). Internal consistency was good for all KSQ modules (Cronbach's a 0.72-0.93). Intraclass correlation coefficients (0.70-0.90) and Bland-Altman plots showed good repeatability of the KSQ. Conclusion: The Dutch KSQ is the first translation of the English KSQ, validated in a Dutch sarcoidosis population.

Original language	English
Pages (from-to)	75-82
Journal	Sarcoidosis Vasculitis and Diffuse Lung Diseases
Volume	33
Issue number	1
Publication status	Published - 2016

Keywords

sarcoidosis
health status
questionnaire
quality of life

Access to Document

Full TextFinal published version, 590 KBLicence: Taverne

Cite this

van Manen, M. J. G., Wapenaar, M., Strookappe, B., Drent, M., Elfferich, M., de Vries, J., Gosker, H. R., Birring, S. S., Patel, A. S., van den Toorn, L., van den Blink, B., Boomars, K., Hoitsma, E., & Wijsenbeek, M. S. (2016). VALIDATION OF THE KING'S SARCOIDOSIS QUESTIONNAIRE (KSQ) IN A DUTCH SARCOIDOSIS POPULATION. Sarcoidosis Vasculitis and Diffuse Lung Diseases, 33(1), 75-82.

@article{4ebab1c7557a48c192aced91bfe01af2,

title = "VALIDATION OF THE KING'S SARCOIDOSIS QUESTIONNAIRE (KSQ) IN A DUTCH SARCOIDOSIS POPULATION",

abstract = "Background: The King's Sarcoidosis Questionnaire (KSQ) is a brief questionnaire assessing health status using five modules (General Health Status, Lung, Medication, Skin, Eyes) in patients with sarcoidosis. The KSQ was only validated in one English sarcoidosis cohort. Objective: The aim of this study was to validate the KSQ in a Dutch sarcoidosis population. Methods: The KSQ was translated according to international guidelines and tested in interviews with patients. Consecutive outpatients completed multiple questionnaires twice, two weeks apart. Construct validity, internal consistency and repeatability were determined. Results: Of the 98 patients included 85 had lung, 22 skin and 24 eye disease. There was good construct validity of the KSQ General Health Status module against the World Health Organization Quality of Life-BREF questionnaire. The Medication module correlated weak to moderate with most questionnaires. The correlations with organ-specific questionnaires varied from strong for Eyes (r=0.75), Skin (r=-0.62) to moderate for Lung (r=-0.45 with MRC breathlessness scale). Internal consistency was good for all KSQ modules (Cronbach's a 0.72-0.93). Intraclass correlation coefficients (0.70-0.90) and Bland-Altman plots showed good repeatability of the KSQ. Conclusion: The Dutch KSQ is the first translation of the English KSQ, validated in a Dutch sarcoidosis population.",

keywords = "sarcoidosis, health status, questionnaire, quality of life",

author = "{van Manen}, {Mirjam J. G.} and Monique Wapenaar and Bert Strookappe and Marjolein Drent and Marjon Elfferich and {de Vries}, Jolanda and Gosker, {Harry R.} and Birring, {Surinder S.} and Patel, {Amit S.} and {van den Toorn}, Leon and {van den Blink}, Bernt and Karin Boomars and Elske Hoitsma and Wijsenbeek, {Marlies S.}",

year = "2016",

language = "English",

volume = "33",

pages = "75--82",

journal = "Sarcoidosis Vasculitis and Diffuse Lung Diseases",

issn = "1124-0490",

publisher = "Mattioli 1885 S.p.A.",

number = "1",

}

TY - JOUR

T1 - VALIDATION OF THE KING'S SARCOIDOSIS QUESTIONNAIRE (KSQ) IN A DUTCH SARCOIDOSIS POPULATION

AU - van Manen, Mirjam J. G.

AU - Wapenaar, Monique

AU - Strookappe, Bert

AU - Drent, Marjolein

AU - Elfferich, Marjon

AU - de Vries, Jolanda

AU - Gosker, Harry R.

AU - Birring, Surinder S.

AU - Patel, Amit S.

AU - van den Toorn, Leon

AU - van den Blink, Bernt

AU - Boomars, Karin

AU - Hoitsma, Elske

AU - Wijsenbeek, Marlies S.

PY - 2016

Y1 - 2016

N2 - Background: The King's Sarcoidosis Questionnaire (KSQ) is a brief questionnaire assessing health status using five modules (General Health Status, Lung, Medication, Skin, Eyes) in patients with sarcoidosis. The KSQ was only validated in one English sarcoidosis cohort. Objective: The aim of this study was to validate the KSQ in a Dutch sarcoidosis population. Methods: The KSQ was translated according to international guidelines and tested in interviews with patients. Consecutive outpatients completed multiple questionnaires twice, two weeks apart. Construct validity, internal consistency and repeatability were determined. Results: Of the 98 patients included 85 had lung, 22 skin and 24 eye disease. There was good construct validity of the KSQ General Health Status module against the World Health Organization Quality of Life-BREF questionnaire. The Medication module correlated weak to moderate with most questionnaires. The correlations with organ-specific questionnaires varied from strong for Eyes (r=0.75), Skin (r=-0.62) to moderate for Lung (r=-0.45 with MRC breathlessness scale). Internal consistency was good for all KSQ modules (Cronbach's a 0.72-0.93). Intraclass correlation coefficients (0.70-0.90) and Bland-Altman plots showed good repeatability of the KSQ. Conclusion: The Dutch KSQ is the first translation of the English KSQ, validated in a Dutch sarcoidosis population.

AB - Background: The King's Sarcoidosis Questionnaire (KSQ) is a brief questionnaire assessing health status using five modules (General Health Status, Lung, Medication, Skin, Eyes) in patients with sarcoidosis. The KSQ was only validated in one English sarcoidosis cohort. Objective: The aim of this study was to validate the KSQ in a Dutch sarcoidosis population. Methods: The KSQ was translated according to international guidelines and tested in interviews with patients. Consecutive outpatients completed multiple questionnaires twice, two weeks apart. Construct validity, internal consistency and repeatability were determined. Results: Of the 98 patients included 85 had lung, 22 skin and 24 eye disease. There was good construct validity of the KSQ General Health Status module against the World Health Organization Quality of Life-BREF questionnaire. The Medication module correlated weak to moderate with most questionnaires. The correlations with organ-specific questionnaires varied from strong for Eyes (r=0.75), Skin (r=-0.62) to moderate for Lung (r=-0.45 with MRC breathlessness scale). Internal consistency was good for all KSQ modules (Cronbach's a 0.72-0.93). Intraclass correlation coefficients (0.70-0.90) and Bland-Altman plots showed good repeatability of the KSQ. Conclusion: The Dutch KSQ is the first translation of the English KSQ, validated in a Dutch sarcoidosis population.

KW - sarcoidosis

KW - health status

KW - questionnaire

KW - quality of life

M3 - Article

SN - 1124-0490

VL - 33

SP - 75

EP - 82

JO - Sarcoidosis Vasculitis and Diffuse Lung Diseases

JF - Sarcoidosis Vasculitis and Diffuse Lung Diseases

IS - 1

ER -