Toenail selenium levels and the risk of breast cancer

P.A. van den Brandt; R.A. Goldbohm; P. van 't Veer; P. Bode; E. Dorant; R.J.J. Hermus; F. Sturmans

doi:10.1093/oxfordjournals.aje.a117155

Toenail selenium levels and the risk of breast cancer

P.A. van den Brandt^*, R.A. Goldbohm, P. van 't Veer, P. Bode, E. Dorant, R.J.J. Hermus, F. Sturmans

^*Corresponding author for this work

NUTRIM School of Nutrition and Translational Research in Metabolism

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Toenail selenium levels and the risk of breast cancer.

van den Brandt PA, Goldbohm RA, van't Veer P, Bode P, Dorant E, Hermus RJ, Sturmans F.

Department of Epidemiology, University of Limburg, Maastricht, The Netherlands.

The association between toenail selenium and breast cancer was studied in a prospective study on diet and cancer among 62,573 Dutch women aged 55-69 years that started in September 1986. The analysis was based on 355 breast cancer cases, detected during 3.3 years of follow-up (1986-1989), for whom selenium data were available. Selenium levels were significantly lower among cases diagnosed early during follow-up. After exclusion of cases that occurred in the first year of follow-up, multivariable-adjusted rate ratios of breast cancer in increasing quintiles of selenium were 1.00, 0.90, 0.76, 0.86, and 0.91 (trend p = 0.618). The authors found no evidence for an inverse association between selenium status and breast cancer

Original language	English
Pages (from-to)	20-26
Journal	American Journal of Epidemiology
Volume	140
Issue number	1
DOIs	https://doi.org/10.1093/oxfordjournals.aje.a117155
Publication status	Published - 1 Jan 1994

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Cite this

@article{99226398c1ae444eb28fc3b16f811f5c,

title = "Toenail selenium levels and the risk of breast cancer",

abstract = "Toenail selenium levels and the risk of breast cancer.van den Brandt PA, Goldbohm RA, van't Veer P, Bode P, Dorant E, Hermus RJ, Sturmans F.Department of Epidemiology, University of Limburg, Maastricht, The Netherlands.The association between toenail selenium and breast cancer was studied in a prospective study on diet and cancer among 62,573 Dutch women aged 55-69 years that started in September 1986. The analysis was based on 355 breast cancer cases, detected during 3.3 years of follow-up (1986-1989), for whom selenium data were available. Selenium levels were significantly lower among cases diagnosed early during follow-up. After exclusion of cases that occurred in the first year of follow-up, multivariable-adjusted rate ratios of breast cancer in increasing quintiles of selenium were 1.00, 0.90, 0.76, 0.86, and 0.91 (trend p = 0.618). The authors found no evidence for an inverse association between selenium status and breast cancer",

author = "{van den Brandt}, P.A. and R.A. Goldbohm and {van 't Veer}, P. and P. Bode and E. Dorant and R.J.J. Hermus and F. Sturmans",

year = "1994",

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T1 - Toenail selenium levels and the risk of breast cancer

AU - van den Brandt, P.A.

AU - Goldbohm, R.A.

AU - van 't Veer, P.

AU - Bode, P.

AU - Dorant, E.

AU - Hermus, R.J.J.

AU - Sturmans, F.

PY - 1994/1/1

Y1 - 1994/1/1

N2 - Toenail selenium levels and the risk of breast cancer.van den Brandt PA, Goldbohm RA, van't Veer P, Bode P, Dorant E, Hermus RJ, Sturmans F.Department of Epidemiology, University of Limburg, Maastricht, The Netherlands.The association between toenail selenium and breast cancer was studied in a prospective study on diet and cancer among 62,573 Dutch women aged 55-69 years that started in September 1986. The analysis was based on 355 breast cancer cases, detected during 3.3 years of follow-up (1986-1989), for whom selenium data were available. Selenium levels were significantly lower among cases diagnosed early during follow-up. After exclusion of cases that occurred in the first year of follow-up, multivariable-adjusted rate ratios of breast cancer in increasing quintiles of selenium were 1.00, 0.90, 0.76, 0.86, and 0.91 (trend p = 0.618). The authors found no evidence for an inverse association between selenium status and breast cancer

AB - Toenail selenium levels and the risk of breast cancer.van den Brandt PA, Goldbohm RA, van't Veer P, Bode P, Dorant E, Hermus RJ, Sturmans F.Department of Epidemiology, University of Limburg, Maastricht, The Netherlands.The association between toenail selenium and breast cancer was studied in a prospective study on diet and cancer among 62,573 Dutch women aged 55-69 years that started in September 1986. The analysis was based on 355 breast cancer cases, detected during 3.3 years of follow-up (1986-1989), for whom selenium data were available. Selenium levels were significantly lower among cases diagnosed early during follow-up. After exclusion of cases that occurred in the first year of follow-up, multivariable-adjusted rate ratios of breast cancer in increasing quintiles of selenium were 1.00, 0.90, 0.76, 0.86, and 0.91 (trend p = 0.618). The authors found no evidence for an inverse association between selenium status and breast cancer

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