TY - JOUR
T1 - Timed performance weaknesses on computerized tasks in pediatric brain tumor survivors
T2 - A comparison with sibling controls
AU - de Ruiter, Marieke Anna
AU - Grootenhuis, Martha Alexandra
AU - van Mourik, Rosa
AU - Maurice-Stam, Heleen
AU - Breteler, Marinus Hermanus Maria
AU - Gidding, Corrie
AU - Beek, Laura Rachel
AU - Granzen, Bernd
AU - van Vuurden, Dannis Gilbert
AU - Schouten-van Meeteren, Antoinette Yvonne Narda
AU - Oosterlaan, Jaap
PY - 2017
Y1 - 2017
N2 - With more children surviving a brain tumor, insight into the late effects of the disease and treatment is of high importance. This study focused on profiling the neurocognitive functions that might be affected after treatment for a pediatric brain tumor, using a broad battery of computerized tests. Predictors that may influence neurocognitive functioning were also investigated. A total of 82 pediatric brain tumor survivors (PBTSs) aged 8-18years (M=13.85, SD=3.15, 49% males) with parent-reported neurocognitive complaints were compared to a control group of 43 siblings (age M=14.27, SD=2.44, 40% males) using linear mixed models. Neurocognitive performance was assessed using measures of attention, processing speed, memory, executive functioning, visuomotor integration (VMI), and intelligence. Tumor type, treatment, tumor location, hydrocephalus, gender, age at diagnosis, and time since diagnosis were entered into regression analyzes as predictors for neurocognitive functioning. The PBTSs showed slower processing speeds and lower intelligence (range effect sizes .71-.82, p
AB - With more children surviving a brain tumor, insight into the late effects of the disease and treatment is of high importance. This study focused on profiling the neurocognitive functions that might be affected after treatment for a pediatric brain tumor, using a broad battery of computerized tests. Predictors that may influence neurocognitive functioning were also investigated. A total of 82 pediatric brain tumor survivors (PBTSs) aged 8-18years (M=13.85, SD=3.15, 49% males) with parent-reported neurocognitive complaints were compared to a control group of 43 siblings (age M=14.27, SD=2.44, 40% males) using linear mixed models. Neurocognitive performance was assessed using measures of attention, processing speed, memory, executive functioning, visuomotor integration (VMI), and intelligence. Tumor type, treatment, tumor location, hydrocephalus, gender, age at diagnosis, and time since diagnosis were entered into regression analyzes as predictors for neurocognitive functioning. The PBTSs showed slower processing speeds and lower intelligence (range effect sizes .71-.82, p
KW - Cancer
KW - brain tumor
KW - attention
KW - speed
KW - memory
KW - ACUTE LYMPHOBLASTIC-LEUKEMIA
KW - WHITE-MATTER INTEGRITY
KW - POSTERIOR-FOSSA TUMORS
KW - WORKING-MEMORY
KW - NEUROPSYCHOLOGICAL PERFORMANCE
KW - NEUROCOGNITIVE CONSEQUENCES
KW - ATTENTIONAL NETWORKS
KW - CRANIAL RADIATION
KW - PRETERM CHILDREN
KW - ADULT SURVIVORS
U2 - 10.1080/09297049.2015.1108395
DO - 10.1080/09297049.2015.1108395
M3 - Article
SN - 0929-7049
VL - 23
SP - 208
EP - 227
JO - Child Neuropsychology
JF - Child Neuropsychology
IS - 2
ER -