The sensitivity of laboratory tests assessing driving related skills to dose-related impairment of alcohol: A literature review

S Jongen*, E F P M Vuurman, J G Ramaekers, A Vermeeren

*Corresponding author for this work

Research output: Contribution to journal(Systematic) Review article peer-review

285 Downloads (Pure)

Abstract

Laboratory tests assessing driving related skills can be useful as initial screening tools to assess potential drug induced impairment as part of a standardized behavioural assessment. Unfortunately, consensus about which laboratory tests should be included to reliably assess drug induced impairment has not yet been reached. The aim of the present review was to evaluate the sensitivity of laboratory tests to the dose dependent effects of alcohol, as a benchmark, on performance parameters. In total, 179 experimental studies were included. Results show that a cued go/no-go task and a divided attention test with primary tracking and secondary visual search were consistently sensitive to the impairing effects at medium and high blood alcohol concentrations. Driving performance assessed in a simulator was less sensitive to the effects of alcohol as compared to naturalistic, on-the-road driving. In conclusion, replicating results of several potentially useful tests and their predictive validity of actual driving impairment should deserve further research. In addition, driving simulators should be validated and compared head to head to naturalistic driving in order to increase construct validity.
Original languageEnglish
Pages (from-to)31-48
Number of pages18
JournalAccident Analysis and Prevention
Volume89
DOIs
Publication statusPublished - Apr 2016

Keywords

  • Alcohol
  • Sensitivity
  • Reliability
  • Laboratory tests
  • Simulator driving
  • Actual driving
  • PLACEBO-CONTROLLED TRIAL
  • PURSUIT EYE-MOVEMENTS
  • RISK-TAKING BEHAVIOR
  • SLEEP LATENCY TEST
  • PSYCHOMOTOR PERFORMANCE
  • HEALTHY-VOLUNTEERS
  • TASK-PERFORMANCE
  • SOCIAL DRINKERS
  • SIMULATOR PERFORMANCE
  • DRIVER IMPAIRMENT

Cite this