@article{be34857037124b8385e91df3437b45b8,
title = "The relationship between childhood trauma and clinical characteristics in ultra-high risk for psychosis youth",
abstract = "Mounting evidence suggests that a history of childhood trauma (CT) is associated with an increased risk of developing a psychotic disorder. Whereas the majority of studies in this area have focused on onset ({"}transition{"}) of psychosis as their primary outcome, few studies have examined the impact of CT on distress associated with attenuated psychotic symptoms (APS) and on diagnostic outcomes other than transition to psychosis. The current study presents data from 81 ultra-high risks (UHR) for psychosis patients who were followed-up for 12 months and who were assessed for a history of CT, severity and distress associated with APS, general psychopathology, functioning and transition to psychosis and/or non-psychotic disorders. The prevalence of childhood trauma in the UHR sample was high (82.7%). Severity of CT was associated with suicidality and self-harm, but, unexpectedly, was unrelated to the other outcomes of the study. The findings stand in contrast with previous UHR studies, which have found CT to be associated with poorer clinical outcomes, poorer functioning, and transition to psychosis and/or other mental disorders. The high prevalence of CT in UHR patients and its association with suicidality and self-harm underlines the importance of inquiring about CT during clinical assessments.",
keywords = "Childhood trauma, ultra-high risk, psychosis, stress, prodrome, ADULT PSYCHIATRIC-DISORDERS, YOUNG-PEOPLE, AT-RISK, SCHIZOPHRENIA, ADVERSITIES, TRANSITION, SYMPTOMS, STRESS, SAMPLE, HALLUCINATIONS",
author = "{de Vos}, Chloe and Andrew Thompson and Paul Amminger and Sarah Bendall and {de Haan}, Lieuwe and Jessica Hartmann and Suzie Lavoie and Connie Markulev and Patrick McGorry and Dorien Nieman and Lisa Phillips and Ulrich Reininghaus and Yuen, {Hok Pan} and Alison Yung and Barnaby Nelson",
note = "Funding Information: The NEURAPRO trial was supported by grants from the Stanley Medical Research Institute (07TGF-1102) and from the National Health and Medical Research Council of Australia (NHMRC; 566529). Dr McGorry was supported by a NHRMC Senior Principal Research Fellowship (1060996), and Drs Amminger, Nelson and Yung were supported by NHMRC Senior Research Fellowships (566593, 1137687 and 1080963 respectively). Dr Hartmann was supported by a University of Melbourne McKenzie Postdoctoral Fellowship. The study was also supported by a Melbourne Health Grant in Aid. The authors would like to acknowledge the many researchers and study staff members involved in the trial globally. The authors would also like to thank all participants for taking part in the study. Funding Information: The NEURAPRO trial was supported by grants from the Stanley Medical Research Institute (07TGF-1102) and from the National Health and Medical Research Council of Australia (NHMRC; 566529). Dr McGorry was supported by a NHRMC Senior Principal Research Fellowship (1060996), and Drs Amminger, Nelson and Yung were supported by NHMRC Senior Research Fellowships (566593, 1137687 and 1080963 respectively). Dr Hartmann was supported by a University of Melbourne McKenzie Postdoctoral Fellowship. The study was also supported by a Melbourne Health Grant in Aid. Publisher Copyright: {\textcopyright} 2019, {\textcopyright} 2019 Informa UK Limited, trading as Taylor & Francis Group.",
year = "2019",
month = jan,
day = "2",
doi = "10.1080/17522439.2019.1582686",
language = "English",
volume = "11",
pages = "28--41",
journal = "Psychosis-Psychological Social and Integrative Approaches",
issn = "1752-2439",
publisher = "Routledge/Taylor & Francis Group",
number = "1",
}