TY - JOUR
T1 - The MOPEAD project
T2 - Advancing patient engagement for the detection of "hidden" undiagnosed cases of Alzheimer's disease in the community
AU - Rodriguez-Gomez, Octavio
AU - Rodrigo, Adrian
AU - Iradier, Fatima
AU - Santos-Santos, Miguel A.
AU - Hundemer, Hans
AU - Ciudin, Andreea
AU - Sannemann, Lena
AU - Zwan, Marissa
AU - Glaysher, Bridget
AU - Wimo, Anders
AU - Bonn, Jaka
AU - Johansson, Gunilla
AU - Rodriguez, Isabel
AU - Alegret, Montse
AU - Gove, Dianne
AU - Pino, Susana
AU - Trigueros, Paloma
AU - Kivipelto, Miia
AU - Mathews, Brandy
AU - Ciudad, Antonio
AU - Ferreira, Daniel
AU - Bintener, Christophe
AU - Gurruchaga, Miren
AU - Westman, Eric
AU - Belger, Mark
AU - Valero, Sergi
AU - Maguire, Peggy
AU - Krivec, David
AU - Kramberger, Milica
AU - Simo, Rafael
AU - Garro, Inmaculada Perez
AU - Visser, Pieter Jelle
AU - Dumas, Annette
AU - Georges, Jean
AU - Jessen, Frank
AU - Winblad, Bengt
AU - Shering, Craig
AU - Stewart, Neil
AU - Campo, Laura
AU - Boada, Merece
AU - MOPEAD Consortium
N1 - Funding Information:
The authors thank Dr. Lutz Froelich for his valuable support as external advisor to the MOPEAD project. This project has received funding from the IMI 2 Joint Undertaking under the grant agreement number 115985 .
Publisher Copyright:
© 2019 The Authors
PY - 2019/6
Y1 - 2019/6
N2 - In most, if not all health systems, dementia is underdiagnosed, and when diagnosis occurs, it is typically at a relatively late stage in the disease process despite mounting evidence showing that a timely diagnosis would result in numerous benefits for patients, families, and society. Moving toward earlier diagnoses in Alzheimer's disease (AD) requires a conscientious and collective effort to implement a global strategy addressing the multiple causes hindering patient engagement at different levels of society. This article describes the design of the Models of Patient Engagement for Alzheimer's Disease project, an ongoing EU-funded public-private multinational initiative that will compare four innovative patient engagement strategies across five European countries regarding their ability to identify individuals with prodromal AD and mild AD dementia, which are "hidden" in their communities and traditionally not found in the typical memory clinic setting. The strategies include an online AD citizen science platform, an open house initiative at the memory clinics, and patient engagement at primary care and diabetologist clinics. (C) 2019 The Authors. Published by Elsevier Inc. on behalf of the Alzheimer's Association. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
AB - In most, if not all health systems, dementia is underdiagnosed, and when diagnosis occurs, it is typically at a relatively late stage in the disease process despite mounting evidence showing that a timely diagnosis would result in numerous benefits for patients, families, and society. Moving toward earlier diagnoses in Alzheimer's disease (AD) requires a conscientious and collective effort to implement a global strategy addressing the multiple causes hindering patient engagement at different levels of society. This article describes the design of the Models of Patient Engagement for Alzheimer's Disease project, an ongoing EU-funded public-private multinational initiative that will compare four innovative patient engagement strategies across five European countries regarding their ability to identify individuals with prodromal AD and mild AD dementia, which are "hidden" in their communities and traditionally not found in the typical memory clinic setting. The strategies include an online AD citizen science platform, an open house initiative at the memory clinics, and patient engagement at primary care and diabetologist clinics. (C) 2019 The Authors. Published by Elsevier Inc. on behalf of the Alzheimer's Association. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
KW - Alzheimer's disease
KW - Early diagnosis
KW - Diagnostic gap
KW - Patient engagement
KW - Population-based screening
KW - Citizen science
KW - COGNITIVE IMPAIRMENT
KW - RISK SCORE
KW - DEMENTIA RISK
KW - OLDER-ADULTS
KW - PREDICTION
KW - DIAGNOSIS
KW - CARE
KW - DECLINE
KW - EUROPE
U2 - 10.1016/j.jalz.2019.02.003
DO - 10.1016/j.jalz.2019.02.003
M3 - (Systematic) Review article
C2 - 31076376
SN - 1552-5260
VL - 15
SP - 828
EP - 839
JO - Alzheimer's & Dementia
JF - Alzheimer's & Dementia
IS - 6
ER -