TY - JOUR
T1 - Serum BDNF Concentrations Show Strong Seasonal Variation and Correlations with the Amount of Ambient Sunlight
AU - Molendijk, Marc L.
AU - Haffmans, Judith P. M.
AU - Bus, Boudewijn A. A.
AU - Spinhoven, Philip
AU - Penninx, Brenda W. J. H.
AU - Prickaerts, Jos
AU - Voshaar, Richard C. Oude
AU - Elzinga, Bernet M.
PY - 2012/11/2
Y1 - 2012/11/2
N2 - Earlier findings show seasonality in processes and behaviors such as brain plasticity and depression that in part are regulated by Brain-Derived Neurotrophic Factor (BDNF). Based on this we investigated seasonal variation in serum BDNF concentrations in 2,851 persons who took part in the Netherlands Study of Depression and Anxiety (NESDA). Analyses by month of sampling (monthly n's >196) showed pronounced seasonal variation in serum BDNF concentrations (P
AB - Earlier findings show seasonality in processes and behaviors such as brain plasticity and depression that in part are regulated by Brain-Derived Neurotrophic Factor (BDNF). Based on this we investigated seasonal variation in serum BDNF concentrations in 2,851 persons who took part in the Netherlands Study of Depression and Anxiety (NESDA). Analyses by month of sampling (monthly n's >196) showed pronounced seasonal variation in serum BDNF concentrations (P
U2 - 10.1371/journal.pone.0048046
DO - 10.1371/journal.pone.0048046
M3 - Article
C2 - 23133609
SN - 1932-6203
VL - 7
JO - PLOS ONE
JF - PLOS ONE
IS - 11
M1 - e48046
ER -