Research output

Self-reported Disability in Patients with Inflammatory Bowel Disease Largely Determined by Disease Activity and Illness Perceptions

Research output: Contribution to journalArticleAcademicpeer-review

Associated researcher

  • ten Have, M.
  • Fidder, H. H.
  • Leenders, M.
  • Kaptein, A. A.
  • van der Valk, M. E.
  • van Bodegraven, A. A.
  • Dijkstra, G.
  • de Jong, D. J.
  • Ponsioen, C. Y.
  • van der Meulen Jong, A. E.
  • van der Woude, C. J.
  • van de Meeberg, P. C.
  • Romberg, M.
  • Clemens, C. H.
  • Jansen, J. M.
  • Mahmmod, N.
  • Bolwerk, C. J.
  • Vermeijden, J. R.
  • Siersema, P. D.
  • Oldenburg, B.

Associated organisations

Abstract

BACKGROUND: The inflammatory bowel disease (IBD) disability index has been introduced to measure patients' physical, psychological, familial, social limitations associated with IBD. We assessed factors related to self-reported disability and the relationship between disability and health care costs. METHODS: A large cohort of patients with Crohn's and ulcerative colitis (UC) was prospectively followed for 2 years by 3 web-based questionnaires. At 2 years, patients completed the IBD index, with lower score indicating more disability. Linear regression was used to examine the impact of demographics, clinical illness perceptions on self-reported disability. Trends in direct health costs across the disability severity groups minimal, mild, moderate, and were tested. RESULTS: A total of 554 patients with CD and 424 patients completed the IBD disability index (response rate, 45%). Both clinical characteristics and illness perceptions significantly contributed to self-reported disability (45%-47%, P = 0.000 and 8%-12%, P = 0.000, respectively). Patients with CD scored lower on the self-reported IBD index than patients with UC (0.255 versus 3.890, P < 0.000), indicating disability in patients with CD. Factors independently associated with self-reported disability rates were increased disease activity, illness (higher number of symptoms attributed to IBD), and stronger emotional Disease duration and disease phenotype were not associated with self- disability. Direct health care costs increased with the worsening of self-reported disability (P = 0.000). CONCLUSIONS: More disability was by patients with CD than by UC. Self-reported disability in IBD was determined by clinical disease activity and illness perceptions but not disease duration or disease phenotype.

    Research areas

  • IBD disability index, illness perceptions, determinants, health care costs, QUALITY-OF-LIFE, INTERNATIONAL CLASSIFICATION, RHEUMATOID-ARTHRITIS, ULCERATIVE-COLITIS, WORK DISABILITY, CROHNS-DISEASE, HEALTH, VALIDATION, PREDICTORS, QUESTIONNAIRE
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Details

Original languageEnglish
Pages (from-to)369-377
Number of pages9
JournalInflammatory Bowel Diseases
Volume21
Issue number2
DOIs
Publication statusPublished - Feb 2015