SAR and scan-time optimized 3D whole-brain double inversion recovery imaging at 7T

Eberhard D Pracht; Thorsten Feiweier; Philipp Ehses; Daniel Brenner; Alard Roebroeck; Bernd Weber; Tony Stöcker

doi:10.1002/mrm.26913

SAR and scan-time optimized 3D whole-brain double inversion recovery imaging at 7T

Eberhard D Pracht^*, Thorsten Feiweier, Philipp Ehses, Daniel Brenner, Alard Roebroeck, Bernd Weber, Tony Stöcker

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

PURPOSE: The aim of this project was to implement an ultra-high field (UHF) optimized double inversion recovery (DIR) sequence for gray matter (GM) imaging, enabling whole brain coverage in short acquisition times ( ≈5 min, image resolution 1 mm(3) ).

METHODS: A 3D variable flip angle DIR turbo spin echo (TSE) sequence was optimized for UHF application. We implemented an improved, fast, and specific absorption rate (SAR) efficient TSE imaging module, utilizing improved reordering. The DIR preparation was tailored to UHF application. Additionally, fat artifacts were minimized by employing water excitation instead of fat saturation.

RESULTS: GM images, covering the whole brain, were acquired in 7 min scan time at 1 mm isotropic resolution. SAR issues were overcome by using a dedicated flip angle calculation considering SAR and SNR efficiency. Furthermore, UHF related artifacts were minimized.

CONCLUSION: The suggested sequence is suitable to generate GM images with whole-brain coverage at UHF. Due to the short total acquisition times and overall robustness, this approach can potentially enable DIR application in a routine setting and enhance lesion detection in neurological diseases. Magn Reson Med, 2017. © 2017 International Society for Magnetic Resonance in Medicine.

Original language	English
Pages (from-to)	2620-2628
Number of pages	9
Journal	Magnetic Resonance in Medicine
Volume	79
Issue number	5
DOIs	https://doi.org/10.1002/mrm.26913
Publication status	Published - May 2018

Keywords

Journal Article
FAST-SPIN-ECHO
FLIP ANGLES
WHITE-MATTER
SAR
PULSE SEQUENCE
DIR
INTRACORTICAL LESIONS
UHF
MULTIPLE-SCLEROSIS
TESLA
MAGNETIC-RESONANCE
EPG
SPATIAL-RESOLUTION
GRAY-MATTER

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10.1002/mrm.26913

Full TextFinal published version, 566 KBLicence: Taverne

Cite this

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title = "SAR and scan-time optimized 3D whole-brain double inversion recovery imaging at 7T",

abstract = "PURPOSE: The aim of this project was to implement an ultra-high field (UHF) optimized double inversion recovery (DIR) sequence for gray matter (GM) imaging, enabling whole brain coverage in short acquisition times ( ≈5 min, image resolution 1 mm(3) ).METHODS: A 3D variable flip angle DIR turbo spin echo (TSE) sequence was optimized for UHF application. We implemented an improved, fast, and specific absorption rate (SAR) efficient TSE imaging module, utilizing improved reordering. The DIR preparation was tailored to UHF application. Additionally, fat artifacts were minimized by employing water excitation instead of fat saturation.RESULTS: GM images, covering the whole brain, were acquired in 7 min scan time at 1 mm isotropic resolution. SAR issues were overcome by using a dedicated flip angle calculation considering SAR and SNR efficiency. Furthermore, UHF related artifacts were minimized.CONCLUSION: The suggested sequence is suitable to generate GM images with whole-brain coverage at UHF. Due to the short total acquisition times and overall robustness, this approach can potentially enable DIR application in a routine setting and enhance lesion detection in neurological diseases. Magn Reson Med, 2017. {\textcopyright} 2017 International Society for Magnetic Resonance in Medicine.",

keywords = "Journal Article, FAST-SPIN-ECHO, FLIP ANGLES, WHITE-MATTER, SAR, PULSE SEQUENCE, DIR, INTRACORTICAL LESIONS, UHF, MULTIPLE-SCLEROSIS, TESLA, MAGNETIC-RESONANCE, EPG, SPATIAL-RESOLUTION, GRAY-MATTER",

author = "Pracht, {Eberhard D} and Thorsten Feiweier and Philipp Ehses and Daniel Brenner and Alard Roebroeck and Bernd Weber and Tony St{\"o}cker",

note = "{\textcopyright} 2017 International Society for Magnetic Resonance in Medicine.",

year = "2018",

month = may,

doi = "10.1002/mrm.26913",

language = "English",

volume = "79",

pages = "2620--2628",

journal = "Magnetic Resonance in Medicine",

issn = "0740-3194",

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number = "5",

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T1 - SAR and scan-time optimized 3D whole-brain double inversion recovery imaging at 7T

AU - Pracht, Eberhard D

AU - Feiweier, Thorsten

AU - Ehses, Philipp

AU - Brenner, Daniel

AU - Roebroeck, Alard

AU - Weber, Bernd

AU - Stöcker, Tony

PY - 2018/5

Y1 - 2018/5

N2 - PURPOSE: The aim of this project was to implement an ultra-high field (UHF) optimized double inversion recovery (DIR) sequence for gray matter (GM) imaging, enabling whole brain coverage in short acquisition times ( ≈5 min, image resolution 1 mm(3) ).METHODS: A 3D variable flip angle DIR turbo spin echo (TSE) sequence was optimized for UHF application. We implemented an improved, fast, and specific absorption rate (SAR) efficient TSE imaging module, utilizing improved reordering. The DIR preparation was tailored to UHF application. Additionally, fat artifacts were minimized by employing water excitation instead of fat saturation.RESULTS: GM images, covering the whole brain, were acquired in 7 min scan time at 1 mm isotropic resolution. SAR issues were overcome by using a dedicated flip angle calculation considering SAR and SNR efficiency. Furthermore, UHF related artifacts were minimized.CONCLUSION: The suggested sequence is suitable to generate GM images with whole-brain coverage at UHF. Due to the short total acquisition times and overall robustness, this approach can potentially enable DIR application in a routine setting and enhance lesion detection in neurological diseases. Magn Reson Med, 2017. © 2017 International Society for Magnetic Resonance in Medicine.

AB - PURPOSE: The aim of this project was to implement an ultra-high field (UHF) optimized double inversion recovery (DIR) sequence for gray matter (GM) imaging, enabling whole brain coverage in short acquisition times ( ≈5 min, image resolution 1 mm(3) ).METHODS: A 3D variable flip angle DIR turbo spin echo (TSE) sequence was optimized for UHF application. We implemented an improved, fast, and specific absorption rate (SAR) efficient TSE imaging module, utilizing improved reordering. The DIR preparation was tailored to UHF application. Additionally, fat artifacts were minimized by employing water excitation instead of fat saturation.RESULTS: GM images, covering the whole brain, were acquired in 7 min scan time at 1 mm isotropic resolution. SAR issues were overcome by using a dedicated flip angle calculation considering SAR and SNR efficiency. Furthermore, UHF related artifacts were minimized.CONCLUSION: The suggested sequence is suitable to generate GM images with whole-brain coverage at UHF. Due to the short total acquisition times and overall robustness, this approach can potentially enable DIR application in a routine setting and enhance lesion detection in neurological diseases. Magn Reson Med, 2017. © 2017 International Society for Magnetic Resonance in Medicine.

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