Role of cis-Monounsaturated Fatty Acids in the Prevention of Coronary Heart Disease

Peter J. Joris; Ronald P. Mensink

doi:10.1007/s11883-016-0597-y

Role of cis-Monounsaturated Fatty Acids in the Prevention of Coronary Heart Disease

Peter J. Joris, Ronald P. Mensink^*

^*Corresponding author for this work

Humane Biologie

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The effects of cis-monounsaturated fatty acids (cis-MUFAs) on the risk of coronary heart disease (CHD) and on CHD mortality are not clear. Also, dietary recommendations for cis-MUFA as derived by various organizations are not in agreement. Earlier studies have mainly focused on the effects of cis-MUFA on serum lipids and lipoproteins. More recent studies, however, have also addressed effects of cis-MUFA on other non-traditional CHD risk markers such as vascular function markers, postprandial vascular function, and energy intake and metabolism. Although well-designed randomized controlled trials with CHD events as endpoints are missing, several large prospective cohort studies have recently been published on the relationship between cis-MUFA and CHD risk. The aim of this paper is to review these new studies that have been published in the last 3 years on the effects of cis-MUFA on cardiovascular risk markers and CHD.

Original language	English
Article number	38
Journal	Current Atherosclerosis Reports
Volume	18
Issue number	7
DOIs	https://doi.org/10.1007/s11883-016-0597-y
Publication status	Published - Jul 2016

Keywords

Monounsaturated fatty acids
Oleic acid
Risk markers
Coronary heart disease
Cardiovascular disease

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10.1007/s11883-016-0597-yLicence: CC BY

Cite this

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title = "Role of cis-Monounsaturated Fatty Acids in the Prevention of Coronary Heart Disease",

abstract = "The effects of cis-monounsaturated fatty acids (cis-MUFAs) on the risk of coronary heart disease (CHD) and on CHD mortality are not clear. Also, dietary recommendations for cis-MUFA as derived by various organizations are not in agreement. Earlier studies have mainly focused on the effects of cis-MUFA on serum lipids and lipoproteins. More recent studies, however, have also addressed effects of cis-MUFA on other non-traditional CHD risk markers such as vascular function markers, postprandial vascular function, and energy intake and metabolism. Although well-designed randomized controlled trials with CHD events as endpoints are missing, several large prospective cohort studies have recently been published on the relationship between cis-MUFA and CHD risk. The aim of this paper is to review these new studies that have been published in the last 3 years on the effects of cis-MUFA on cardiovascular risk markers and CHD.",

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