Risk factors for mortality and failure of conservative treatment after aortic type B dissection

Jochen Grommes; Andreas Greiner; Bianca Bendermacher; Max Erlmeier; Andreas Frech; Perrine Belau; Lieven N. Kennes; Gustav Fraedrich; Geert Wilhelm Schurink; Michael J. Jacobs; Josef Klocker

doi:10.1016/j.jtcvs.2014.03.053

Risk factors for mortality and failure of conservative treatment after aortic type B dissection

Jochen Grommes^*, Andreas Greiner, Bianca Bendermacher, Max Erlmeier, Andreas Frech, Perrine Belau, Lieven N. Kennes, Gustav Fraedrich, Geert Wilhelm Schurink, Michael J. Jacobs, Josef Klocker

^*Corresponding author for this work

Surgery

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Despite medical treatment, one third of patients with uncomplicated type B aortic dissections experience severe late complications. The aim of this study was to identify patients at high risk of mortality during follow-up.A total of 183 patients with acute Stanford type B dissection were treated in one of the university hospitals (Aachen [Germany], Maastricht [The Netherlands], and Innsbruck [Austria]) between 1997 and 2010. Records indicated that 120 patients were treated conservatively. Of these patients, 16 were lost to follow-up. The maximum diameter, extent of the dissection, and patency of the side branches were determined from computed tomography angiography data. Survival and treatment failure were analyzed by univariate and multivariate Cox regression analysis. The univariate analysis investigated the influence of aortic diameter (?41 vs

Original language	English
Pages (from-to)	2155-2160.e1
Journal	Journal of Thoracic and Cardiovascular Surgery
Volume	148
Issue number	5
DOIs	https://doi.org/10.1016/j.jtcvs.2014.03.053
Publication status	Published - Nov 2014

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10.1016/j.jtcvs.2014.03.053Licence: Free access - publisher

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Grommes, J., Greiner, A., Bendermacher, B., Erlmeier, M., Frech, A., Belau, P., Kennes, L. N., Fraedrich, G., Schurink, G. W., Jacobs, M. J., & Klocker, J. (2014). Risk factors for mortality and failure of conservative treatment after aortic type B dissection. Journal of Thoracic and Cardiovascular Surgery, 148(5), 2155-2160.e1. https://doi.org/10.1016/j.jtcvs.2014.03.053

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abstract = "Despite medical treatment, one third of patients with uncomplicated type B aortic dissections experience severe late complications. The aim of this study was to identify patients at high risk of mortality during follow-up.A total of 183 patients with acute Stanford type B dissection were treated in one of the university hospitals (Aachen [Germany], Maastricht [The Netherlands], and Innsbruck [Austria]) between 1997 and 2010. Records indicated that 120 patients were treated conservatively. Of these patients, 16 were lost to follow-up. The maximum diameter, extent of the dissection, and patency of the side branches were determined from computed tomography angiography data. Survival and treatment failure were analyzed by univariate and multivariate Cox regression analysis. The univariate analysis investigated the influence of aortic diameter (?41 vs ",

author = "Jochen Grommes and Andreas Greiner and Bianca Bendermacher and Max Erlmeier and Andreas Frech and Perrine Belau and Kennes, {Lieven N.} and Gustav Fraedrich and Schurink, {Geert Wilhelm} and Jacobs, {Michael J.} and Josef Klocker",

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doi = "10.1016/j.jtcvs.2014.03.053",

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AU - Grommes, Jochen

AU - Greiner, Andreas

AU - Bendermacher, Bianca

AU - Erlmeier, Max

AU - Frech, Andreas

AU - Belau, Perrine

AU - Kennes, Lieven N.

AU - Fraedrich, Gustav

AU - Schurink, Geert Wilhelm

AU - Jacobs, Michael J.

AU - Klocker, Josef

PY - 2014/11

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N2 - Despite medical treatment, one third of patients with uncomplicated type B aortic dissections experience severe late complications. The aim of this study was to identify patients at high risk of mortality during follow-up.A total of 183 patients with acute Stanford type B dissection were treated in one of the university hospitals (Aachen [Germany], Maastricht [The Netherlands], and Innsbruck [Austria]) between 1997 and 2010. Records indicated that 120 patients were treated conservatively. Of these patients, 16 were lost to follow-up. The maximum diameter, extent of the dissection, and patency of the side branches were determined from computed tomography angiography data. Survival and treatment failure were analyzed by univariate and multivariate Cox regression analysis. The univariate analysis investigated the influence of aortic diameter (?41 vs

AB - Despite medical treatment, one third of patients with uncomplicated type B aortic dissections experience severe late complications. The aim of this study was to identify patients at high risk of mortality during follow-up.A total of 183 patients with acute Stanford type B dissection were treated in one of the university hospitals (Aachen [Germany], Maastricht [The Netherlands], and Innsbruck [Austria]) between 1997 and 2010. Records indicated that 120 patients were treated conservatively. Of these patients, 16 were lost to follow-up. The maximum diameter, extent of the dissection, and patency of the side branches were determined from computed tomography angiography data. Survival and treatment failure were analyzed by univariate and multivariate Cox regression analysis. The univariate analysis investigated the influence of aortic diameter (?41 vs

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