Reperfusion cardiac arrhythmias and their relation to reperfusion induced cell death

Kirian van der Weg

Research output: ThesisDoctoral ThesisInternal

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Abstract

The aim of this dissertation was to analyse why cardiac arrhythmias occur after opening of the coronary arteries when a patient suffers an acute myocardial infarction. During this event, the heart muscle sustains damage due to a lack of oxygen. It was hypothesised that these arrhythmias indicate extra damage due to the reperfusion of oxygen-deprived heart muscle tissue. This is called a reperfusion injury. Cardiac arrhythmias could be the first marker of reperfusion injury. This marker could be used to indicate and develop treatment options for this type of injury.
Original languageEnglish
Awarding Institution
  • Maastricht University
Supervisors/Advisors
  • Gorgels, Antonius, Supervisor
  • Krucoff, Mitchell W., Supervisor, External person
  • de Winter, Robbert J., Supervisor, External person
Award date21 Dec 2018
Place of PublicationMaastricht
Publisher
Print ISBNs9789463801409
DOIs
Publication statusPublished - 2018

Keywords

  • myocardial infarction
  • arrhythmia
  • reperfusion injury
  • diagnostic tool

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