TY - JOUR
T1 - Radiomics: Extracting more information from medical images using advanced feature analysis
AU - Lambin, Philippe
AU - Rios-Velazquez, Emmanuel
AU - Leijenaar, Ralph
AU - Carvalho, Sara
AU - van Stiphout, Ruud G. P. M.
AU - Granton, Patrick
AU - Zegers, Catharina M. L.
AU - Gillies, Robert
AU - Boellard, Ronald
AU - Dekker, Andre
AU - Aerts, Hugo J. W. L.
PY - 2012/3
Y1 - 2012/3
N2 - Solid cancers are spatially and temporally heterogeneous. This limits the use of invasive biopsy based molecular assays but gives huge potential for medical imaging, which has the ability to capture intra-tumoural heterogeneity in a non-invasive way. During the past decades, medical imaging innovations with new hardware, new imaging agents and standardised protocols, allows the field to move towards quantitative imaging. Therefore, also the development of automated and reproducible analysis methodologies to extract more information from image-based features is a requirement. Radiomics - the high-throughput extraction of large amounts of image features from radiographic images - addresses this problem and is one of the approaches that hold great promises but need further validation in multi-centric settings and in the laboratory.
AB - Solid cancers are spatially and temporally heterogeneous. This limits the use of invasive biopsy based molecular assays but gives huge potential for medical imaging, which has the ability to capture intra-tumoural heterogeneity in a non-invasive way. During the past decades, medical imaging innovations with new hardware, new imaging agents and standardised protocols, allows the field to move towards quantitative imaging. Therefore, also the development of automated and reproducible analysis methodologies to extract more information from image-based features is a requirement. Radiomics - the high-throughput extraction of large amounts of image features from radiographic images - addresses this problem and is one of the approaches that hold great promises but need further validation in multi-centric settings and in the laboratory.
KW - Imaging
KW - Radiomics
KW - Tumour
KW - Intra tumour heterogeneity
U2 - 10.1016/j.ejca.2011.11.036
DO - 10.1016/j.ejca.2011.11.036
M3 - Article
SN - 0959-8049
VL - 48
SP - 441
EP - 446
JO - European Journal of Cancer
JF - European Journal of Cancer
IS - 4
ER -