@article{b5279a6452c14ce7a747aaa78290f2be,
title = "Opposing Age-Related Trends in Absolute and Relative Risk of Adverse Health Outcomes Associated With Out-of-Office Blood Pressure",
abstract = "Participant-level meta-analyses assessed the age-specific relevance of office blood pressure to cardiovascular complications, but this information is lacking for out-of-office blood pressure. At baseline, daytime ambulatory (n=12 624) or home (n=5297) blood pressure were measured in 17 921 participants (51.3% women; mean age, 54.2 years) from 17 population cohorts. Subsequently, mortality and cardiovascular events were recorded. Using multivariable Cox regression, floating absolute risk was computed across 4 age bands (80 years). Over 236 491 person-years, 3855 people died and 2942 cardiovascular events occurred. From levels as low as 110/65 mm Hg, risk log-linearly increased with higher out-of-office systolic/diastolic blood pressure. From the youngest to the oldest age group, rates expressed per 1000 person-years increased (P",
keywords = "BASE-LINE CHARACTERISTICS, CARDIOVASCULAR RISK, HOME, HYPERTENSION, INTERNATIONAL DATABASE, METAANALYSIS, MILLION ADULTS, MORTALITY, POPULATION, PREDICTION, STROKE, TASK-FORCE, ambulatory, blood pressure, blood pressure monitoring, cardiovascular diseases, hypertension, mortality",
author = "Yan Li and Lutgarde Thijs and Zhen-Yu Zhang and Kei Asayama and Hansen, {Tine W.} and Jose Boggia and Kristina Bjoerklund-Bodegard and Wen-Yi Yang and Niiranen, {Teemu J.} and Angeliki Ntineri and Fang-Fei Wei and Masahiro Kikuya and Takayoshi Ohkubo and Eamon Dolan and Atsushi Hozawa and Ichiro Tsuji and Katarzyna Stolarz-Skrzypek and Qi-Fang Huang and Melgarejo, {Jesus D.} and Valerie Tikhonoff and Sofia Malyutina and Edoardo Casiglia and Yuri Nikitin and Lars Lind and Edgardo Sandoya and Lucas Aparicio and Jessica Barochiner and Natasza Gilis-Malinowska and Krzysztof Narkiewicz and Kalina Kawecka-Jaszcz and Maestre, {Gladys E.} and Jula, {Antti M.} and Johansson, {Jouni K.} and Tatiana Kuznetsova and Jan Filipovsky and George Stergiou and Ji-Guang Wang and Yutaka Imai and Eoin O'Brien and Staessen, {Jan A.} and {International Database on Ambulatory and Home Blood Pressure in Relation to Cardiovascular Outcome Investigators}",
note = "Publisher Copyright: {\textcopyright} 2019 American Heart Association, Inc.",
year = "2019",
month = dec,
doi = "10.1161/HYPERTENSIONAHA.119.12958",
language = "English",
volume = "74",
pages = "1333--1342",
journal = "Hypertension",
issn = "0194-911X",
publisher = "LIPPINCOTT WILLIAMS & WILKINS",
number = "6",
}