TY - JOUR
T1 - Multicenter CT phantoms public dataset for radiomics reproducibility tests
AU - Kalendralis, Petros
AU - Traverso, Alberto
AU - Shi, Zhenwei
AU - Zhovannik, Ivan
AU - Monshouwer, Rene
AU - Starmans, Martijn P. A.
AU - Klein, Stefan
AU - Pfaehler, Elisabeth
AU - Boellaard, Ronald
AU - Dekker, Andre
AU - Wee, Leonard
N1 - Funding Information:
The authors thank the in-kind contribution of the commercial vendors, Computerized Imaging Reference Systems (CIRS) and The Phantom Laboratory, that supported our study with the loan of the above mentioned phantoms. The commercial partners have made no direct contribution to the writing of this article. This work has been carried out as part of the Dutch STW-Perspectief Research Program (STRaTeGy grant numbers 14929 and 14930). The national research infrastructure TraIT is being financially supported by the Dutch Cancer Society.
Publisher Copyright:
© 2019 The Authors Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.
PY - 2019/3
Y1 - 2019/3
N2 - Purpose The aim of this paper is to describe a public, open-access, computed tomography (CT) phantom image set acquired at three centers and collected especially for radiomics reproducibility research. The dataset is useful to test radiomic features reproducibility with respect to various parameters, such as acquisition settings, scanners, and reconstruction algorithms. Acquisition and validation methods Three phantoms were scanned in three independent institutions. Images of the following phantoms were acquired: Catphan 700 and COPDGene Phantom II (Phantom Laboratory, Greenwich, NY, USA), and the Triple modality 3D Abdominal Phantom (CIRS, Norfolk, VA, USA). Data were collected at three Dutch medical centers: MAASTRO Clinic (Maastricht, NL), Radboud University Medical Center (Nijmegen, NL), and University Medical Center Groningen (Groningen, NL) with scanners from two different manufacturers Siemens Healthcare and Philips Healthcare. The following acquisition parameter were varied in the phantom scans: slice thickness, reconstruction kernels, and tube current. Data format and usage notes We made the dataset publically available on the Dutch instance of "Extensible Neuroimaging Archive Toolkit-XNAT" (). The dataset is freely available and reusable with attribution (Creative Commons 3.0 license). Potential applications Our goal was to provide a findable, open-access, annotated, and reusable CT phantom dataset for radiomics reproducibility studies. Reproducibility testing and harmonization are fundamental requirements for wide generalizability of radiomics-based clinical prediction models. It is highly desirable to include only reproducible features into models, to be more assured of external validity across hitherto unseen contexts. In this view, phantom data from different centers represent a valuable source of information to exclude CT radiomic features that may already be unstable with respect to simplified structures and tightly controlled scan settings. The intended extension of our shared dataset is to include other modalities and phantoms with more realistic lesion simulations.
AB - Purpose The aim of this paper is to describe a public, open-access, computed tomography (CT) phantom image set acquired at three centers and collected especially for radiomics reproducibility research. The dataset is useful to test radiomic features reproducibility with respect to various parameters, such as acquisition settings, scanners, and reconstruction algorithms. Acquisition and validation methods Three phantoms were scanned in three independent institutions. Images of the following phantoms were acquired: Catphan 700 and COPDGene Phantom II (Phantom Laboratory, Greenwich, NY, USA), and the Triple modality 3D Abdominal Phantom (CIRS, Norfolk, VA, USA). Data were collected at three Dutch medical centers: MAASTRO Clinic (Maastricht, NL), Radboud University Medical Center (Nijmegen, NL), and University Medical Center Groningen (Groningen, NL) with scanners from two different manufacturers Siemens Healthcare and Philips Healthcare. The following acquisition parameter were varied in the phantom scans: slice thickness, reconstruction kernels, and tube current. Data format and usage notes We made the dataset publically available on the Dutch instance of "Extensible Neuroimaging Archive Toolkit-XNAT" (). The dataset is freely available and reusable with attribution (Creative Commons 3.0 license). Potential applications Our goal was to provide a findable, open-access, annotated, and reusable CT phantom dataset for radiomics reproducibility studies. Reproducibility testing and harmonization are fundamental requirements for wide generalizability of radiomics-based clinical prediction models. It is highly desirable to include only reproducible features into models, to be more assured of external validity across hitherto unseen contexts. In this view, phantom data from different centers represent a valuable source of information to exclude CT radiomic features that may already be unstable with respect to simplified structures and tightly controlled scan settings. The intended extension of our shared dataset is to include other modalities and phantoms with more realistic lesion simulations.
KW - FEATURES
KW - IMAGES
U2 - 10.1002/mp.13385
DO - 10.1002/mp.13385
M3 - Article
C2 - 30629299
SN - 0094-2405
VL - 46
SP - 1512
EP - 1518
JO - Medical Physics
JF - Medical Physics
IS - 3
ER -