MR Angiography of Collateral Arteries in a Hind Limb Ischemia Model: Comparison between Blood Pool Agent Gadomer and Small Contrast Agent Gd-DTPA

Karolien Jaspers; Bas Versluis; Tim Leiner; Petra Dijkstra; Marlies Oostendorp; Jolanda M. van Golde; Mark J. Post; Walter H. Backes

doi:10.1371/journal.pone.0016159

MR Angiography of Collateral Arteries in a Hind Limb Ischemia Model: Comparison between Blood Pool Agent Gadomer and Small Contrast Agent Gd-DTPA

Karolien Jaspers^*, Bas Versluis, Tim Leiner, Petra Dijkstra, Marlies Oostendorp, Jolanda M. van Golde, Mark J. Post, Walter H. Backes

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The objective of this study was to compare the blood pool agent Gadomer with a small contrast agent for the visualization of ultra-small, collateral arteries (diameter0.10). Inter-observer variation was 24% and 18% for Gadomer and Gd-DTPA, respectively. In conclusion, blood pool agent Gadomer improved vessel conspicuity compared to Gd-DTPA. Steady-state MRA can be considered as an excellent non-invasive alternative to intra-arterial XRA for the visualization of ultra-small collateral arteries.

Original language	English
Pages (from-to)	6
Journal	PLOS ONE
Volume	6
Issue number	1
DOIs	https://doi.org/10.1371/journal.pone.0016159
Publication status	Published - 26 Jan 2011

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10.1371/journal.pone.0016159Licence: CC BY

Cite this

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title = "MR Angiography of Collateral Arteries in a Hind Limb Ischemia Model: Comparison between Blood Pool Agent Gadomer and Small Contrast Agent Gd-DTPA",

abstract = "The objective of this study was to compare the blood pool agent Gadomer with a small contrast agent for the visualization of ultra-small, collateral arteries (diameter0.10). Inter-observer variation was 24% and 18% for Gadomer and Gd-DTPA, respectively. In conclusion, blood pool agent Gadomer improved vessel conspicuity compared to Gd-DTPA. Steady-state MRA can be considered as an excellent non-invasive alternative to intra-arterial XRA for the visualization of ultra-small collateral arteries.",

author = "Karolien Jaspers and Bas Versluis and Tim Leiner and Petra Dijkstra and Marlies Oostendorp and {van Golde}, {Jolanda M.} and Post, {Mark J.} and Backes, {Walter H.}",

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AU - Jaspers, Karolien

AU - Versluis, Bas

AU - Leiner, Tim

AU - Dijkstra, Petra

AU - Oostendorp, Marlies

AU - van Golde, Jolanda M.

AU - Post, Mark J.

AU - Backes, Walter H.

PY - 2011/1/26

Y1 - 2011/1/26

N2 - The objective of this study was to compare the blood pool agent Gadomer with a small contrast agent for the visualization of ultra-small, collateral arteries (diameter0.10). Inter-observer variation was 24% and 18% for Gadomer and Gd-DTPA, respectively. In conclusion, blood pool agent Gadomer improved vessel conspicuity compared to Gd-DTPA. Steady-state MRA can be considered as an excellent non-invasive alternative to intra-arterial XRA for the visualization of ultra-small collateral arteries.

AB - The objective of this study was to compare the blood pool agent Gadomer with a small contrast agent for the visualization of ultra-small, collateral arteries (diameter0.10). Inter-observer variation was 24% and 18% for Gadomer and Gd-DTPA, respectively. In conclusion, blood pool agent Gadomer improved vessel conspicuity compared to Gd-DTPA. Steady-state MRA can be considered as an excellent non-invasive alternative to intra-arterial XRA for the visualization of ultra-small collateral arteries.

U2 - 10.1371/journal.pone.0016159

DO - 10.1371/journal.pone.0016159

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