Microelectrode Recording for Deep Brain Stimulation of the Subthalamic Nucleus in Patients with Advanced Parkinson's Disease: Advantage or Loss of Time?

Ersoy Kocabicak; Onur Alptekin; Dursun Aygun; Onur Yildiz; Yasin Temel

doi:10.5137/1019-5149.JTN.23307-18.3

Microelectrode Recording for Deep Brain Stimulation of the Subthalamic Nucleus in Patients with Advanced Parkinson's Disease: Advantage or Loss of Time?

Ersoy Kocabicak^*, Onur Alptekin^*, Dursun Aygun, Onur Yildiz, Yasin Temel

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

AIM: To investigate the effect of using microelectrode recording (MER) on the length of time required to carry out a deep brain stimulation (DBS) procedure of the subthalamic nucleus in patients with Parkinson's disease (PD).

MATERIAL and METHODS: The time required to include MER in the DBS operation was calculated for the first and second sides in 24 patients with PD. The number of microelectrodes used on each trajectory for the first and second sides, and the percentage of permanent electrodes implanted on each trajectory for the first and second sides, were quantified.

RESULTS: The average times taken to use MER were 23.4 +/- 6.2 minutes, 17.4 +/- 6.5 minutes, and 41.2 +/- 6.3 minutes for the first side, second side and total procedure, respectively. In 75% of patients, the permanent electrode was implanted at the planned target site for the first side, and in 61% of patients for the second side.

CONCLUSION: MER extends the time required to carry out the DBS procedure. However, during surgery, it provides real-time information on the electrodes' neurophysiological locations and helps the surgical team choose an alternative target if the planned target does not produce satisfying results.

Original language	English
Pages (from-to)	677-682
Number of pages	6
Journal	Turkish Neurosurgery
Volume	29
Issue number	5
DOIs	https://doi.org/10.5137/1019-5149.JTN.23307-18.3
Publication status	Published - 2019

Keywords

Microelectrode recording
Subthalamic nucleus
Deep brain stimulation
Parkinson's disease
HARDWARE-RELATED COMPLICATIONS
ELECTRICAL-STIMULATION
HEMORRHAGE
SURGERY
RISK
MRI

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10.5137/1019-5149.JTN.23307-18.3

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@article{feb2220575904bd2bbf9a60662aede5e,

title = "Microelectrode Recording for Deep Brain Stimulation of the Subthalamic Nucleus in Patients with Advanced Parkinson's Disease: Advantage or Loss of Time?",

abstract = "AIM: To investigate the effect of using microelectrode recording (MER) on the length of time required to carry out a deep brain stimulation (DBS) procedure of the subthalamic nucleus in patients with Parkinson's disease (PD).MATERIAL and METHODS: The time required to include MER in the DBS operation was calculated for the first and second sides in 24 patients with PD. The number of microelectrodes used on each trajectory for the first and second sides, and the percentage of permanent electrodes implanted on each trajectory for the first and second sides, were quantified.RESULTS: The average times taken to use MER were 23.4 +/- 6.2 minutes, 17.4 +/- 6.5 minutes, and 41.2 +/- 6.3 minutes for the first side, second side and total procedure, respectively. In 75% of patients, the permanent electrode was implanted at the planned target site for the first side, and in 61% of patients for the second side.CONCLUSION: MER extends the time required to carry out the DBS procedure. However, during surgery, it provides real-time information on the electrodes' neurophysiological locations and helps the surgical team choose an alternative target if the planned target does not produce satisfying results.",

keywords = "Microelectrode recording, Subthalamic nucleus, Deep brain stimulation, Parkinson's disease, HARDWARE-RELATED COMPLICATIONS, ELECTRICAL-STIMULATION, HEMORRHAGE, SURGERY, RISK, MRI",

author = "Ersoy Kocabicak and Onur Alptekin and Dursun Aygun and Onur Yildiz and Yasin Temel",

note = "Publisher Copyright: {\textcopyright} 2019, Turkish Neurosurgical Society.",

year = "2019",

doi = "10.5137/1019-5149.JTN.23307-18.3",

language = "English",

volume = "29",

pages = "677--682",

journal = "Turkish Neurosurgery",

issn = "1019-5149",

publisher = "Turkish Neurosurgical Society",

number = "5",

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TY - JOUR

T1 - Microelectrode Recording for Deep Brain Stimulation of the Subthalamic Nucleus in Patients with Advanced Parkinson's Disease

T2 - Advantage or Loss of Time?

AU - Kocabicak, Ersoy

AU - Alptekin, Onur

AU - Aygun, Dursun

AU - Yildiz, Onur

AU - Temel, Yasin

PY - 2019

Y1 - 2019

N2 - AIM: To investigate the effect of using microelectrode recording (MER) on the length of time required to carry out a deep brain stimulation (DBS) procedure of the subthalamic nucleus in patients with Parkinson's disease (PD).MATERIAL and METHODS: The time required to include MER in the DBS operation was calculated for the first and second sides in 24 patients with PD. The number of microelectrodes used on each trajectory for the first and second sides, and the percentage of permanent electrodes implanted on each trajectory for the first and second sides, were quantified.RESULTS: The average times taken to use MER were 23.4 +/- 6.2 minutes, 17.4 +/- 6.5 minutes, and 41.2 +/- 6.3 minutes for the first side, second side and total procedure, respectively. In 75% of patients, the permanent electrode was implanted at the planned target site for the first side, and in 61% of patients for the second side.CONCLUSION: MER extends the time required to carry out the DBS procedure. However, during surgery, it provides real-time information on the electrodes' neurophysiological locations and helps the surgical team choose an alternative target if the planned target does not produce satisfying results.

AB - AIM: To investigate the effect of using microelectrode recording (MER) on the length of time required to carry out a deep brain stimulation (DBS) procedure of the subthalamic nucleus in patients with Parkinson's disease (PD).MATERIAL and METHODS: The time required to include MER in the DBS operation was calculated for the first and second sides in 24 patients with PD. The number of microelectrodes used on each trajectory for the first and second sides, and the percentage of permanent electrodes implanted on each trajectory for the first and second sides, were quantified.RESULTS: The average times taken to use MER were 23.4 +/- 6.2 minutes, 17.4 +/- 6.5 minutes, and 41.2 +/- 6.3 minutes for the first side, second side and total procedure, respectively. In 75% of patients, the permanent electrode was implanted at the planned target site for the first side, and in 61% of patients for the second side.CONCLUSION: MER extends the time required to carry out the DBS procedure. However, during surgery, it provides real-time information on the electrodes' neurophysiological locations and helps the surgical team choose an alternative target if the planned target does not produce satisfying results.

KW - Microelectrode recording

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KW - Deep brain stimulation

KW - Parkinson's disease

KW - HARDWARE-RELATED COMPLICATIONS

KW - ELECTRICAL-STIMULATION

KW - HEMORRHAGE

KW - SURGERY

KW - RISK

KW - MRI

U2 - 10.5137/1019-5149.JTN.23307-18.3

DO - 10.5137/1019-5149.JTN.23307-18.3

M3 - Article

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SN - 1019-5149

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JO - Turkish Neurosurgery

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