TY - JOUR
T1 - Long-term changes in visual outcomes and ocular morphometrics after myopic and toric phakic intraocular lens implantation
T2 - Five- and 10-year results
AU - Jonker, Soraya M. R.
AU - Berendschot, Tos T. J. M.
AU - Ronden, Annick E.
AU - Saelens, Isabelle E. Y.
AU - Bauer, Noel J. C.
AU - Nuijts, Rudy M. M. A.
N1 - Funding Information:
Dr. Bauer receives grants and personal fees from Alcon Laboratories, Inc., personal fees from Bausch + Lomb, Inc. , and grants from Ophtec BV outside the submitted work. Dr. Nuijts receives grants from Abbott Medical Optics , Inc., Bausch & Lomb, Inc. , Carl Zeiss Meditec AG , HumanOptics AG, Oculentis GmbH, Ophtec BV, grants and personal fees from Alcon Laboratories, Inc., and personal fees from ASICO LLC and Théa Pharma GmbH outside the submitted work. None of the other authors has a financial or proprietary interest in any material or method mentioned.
Funding Information:
Dr. Bauer receives grants and personal fees from Alcon Laboratories, Inc., personal fees from Bausch + Lomb, Inc., and grants from Ophtec BV outside the submitted work. Dr. Nuijts receives grants from Abbott Medical Optics, Inc., Bausch & Lomb, Inc., Carl Zeiss Meditec AG, HumanOptics AG, Oculentis GmbH, Ophtec BV, grants and personal fees from Alcon Laboratories, Inc., and personal fees from ASICO LLC and Th?a Pharma GmbH outside the submitted work. None of the other authors has a financial or proprietary interest in any material or method mentioned.
Publisher Copyright:
© 2019 ASCRS and ESCRS
PY - 2019/10
Y1 - 2019/10
N2 - Purpose: To evaluate the long-term refractive and visual, anterior chamber depth, and axial length (AL) changes and complications after rigid iris-fixated phakic intraocular lens (pIOL) implantation to treat myopia or astigmatism.Setting: University Eye Clinic Maastricht, Maastricht UMC + , the Netherlands.Design: Prospective case series.Methods: The study evaluated patients who had implantation of an Artisan myopic or toric iris-fixated pIOL as of January 1998. Changes were measured annually and reported after 1, 5, and 10 years postoperatively.Results: The study comprised 460 eyes (250 patients; mean age 41.1 years +/- 10.7 [SD]). Over 10 years, the mean myopization was -0.79 diopters (D) (P <.001), with 52% of eyes within +/- 1.0 D of target. The mean increase in the logarithm of the minimum angle of resolution (logMAR) corrected distance visual acuity (CDVA) over 10 years was 0.05 (P <.001); 95% of eyes had a CDVA of 20/40 or more and 7% lost 2 or more lines of CDVA. The mean logMAR uncorrected visual acuity (UDVA) increased by 0.14 over 10 years (P <.001); 96% had a UDVA 20/40 or better. The AL increased by 1.14 mm over 10 years (P = .009). Ten percent of pIOLs were explanted because of cataract formation after a mean of 97.9 +/- 34.9 months. A higher preoperative age (hazard ratio [HR], 1.08; P <.001) and longer AL (HR, 1.34; P <.001) were risk factors for shorter survival because of cataract formation.Conclusion: Ten years after rigid iris-fixated pIOL implantation, the CDVA and UDVA decreased significantly as a result of significant myopization caused by an increased AL unrelated to the pIOL. (C) 2019 ASCRS and ESCRS
AB - Purpose: To evaluate the long-term refractive and visual, anterior chamber depth, and axial length (AL) changes and complications after rigid iris-fixated phakic intraocular lens (pIOL) implantation to treat myopia or astigmatism.Setting: University Eye Clinic Maastricht, Maastricht UMC + , the Netherlands.Design: Prospective case series.Methods: The study evaluated patients who had implantation of an Artisan myopic or toric iris-fixated pIOL as of January 1998. Changes were measured annually and reported after 1, 5, and 10 years postoperatively.Results: The study comprised 460 eyes (250 patients; mean age 41.1 years +/- 10.7 [SD]). Over 10 years, the mean myopization was -0.79 diopters (D) (P <.001), with 52% of eyes within +/- 1.0 D of target. The mean increase in the logarithm of the minimum angle of resolution (logMAR) corrected distance visual acuity (CDVA) over 10 years was 0.05 (P <.001); 95% of eyes had a CDVA of 20/40 or more and 7% lost 2 or more lines of CDVA. The mean logMAR uncorrected visual acuity (UDVA) increased by 0.14 over 10 years (P <.001); 96% had a UDVA 20/40 or better. The AL increased by 1.14 mm over 10 years (P = .009). Ten percent of pIOLs were explanted because of cataract formation after a mean of 97.9 +/- 34.9 months. A higher preoperative age (hazard ratio [HR], 1.08; P <.001) and longer AL (HR, 1.34; P <.001) were risk factors for shorter survival because of cataract formation.Conclusion: Ten years after rigid iris-fixated pIOL implantation, the CDVA and UDVA decreased significantly as a result of significant myopization caused by an increased AL unrelated to the pIOL. (C) 2019 ASCRS and ESCRS
KW - IN-SITU KERATOMILEUSIS
KW - RETINAL-DETACHMENT
KW - ANTERIOR SEGMENT
KW - FOLLOW-UP
KW - CATARACT
KW - MODERATE
KW - ASTIGMATISM
KW - SURGERY
KW - EYES
KW - AGE
U2 - 10.1016/j.jcrs.2019.05.044
DO - 10.1016/j.jcrs.2019.05.044
M3 - Article
C2 - 31564321
SN - 0886-3350
VL - 45
SP - 1470
EP - 1479
JO - Journal of Cataract and Refractive Surgery
JF - Journal of Cataract and Refractive Surgery
IS - 10
ER -