Interictal cortical reorganization in episodic migraine without aura: an event-related fMRI study during parametric trigeminal nociceptive stimulation

A. Tessitore; A. Russo; F. Esposito; A. Giordano; G. Taglialatela; R. De Micco; M. Cirillo; F. Conte; F. d'Onofrio; S. Cirillo; G. Tedeschi

doi:10.1007/s10072-011-0537-0

Interictal cortical reorganization in episodic migraine without aura: an event-related fMRI study during parametric trigeminal nociceptive stimulation

A. Tessitore, A. Russo, F. Esposito, A. Giordano, G. Taglialatela, R. De Micco, M. Cirillo, F. Conte, F. d'Onofrio, S. Cirillo, G. Tedeschi^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The aim of our study was to explore the pain processing network in patients with migraine during trigeminal nociceptive stimulation. Sixteen patients with episodic migraine without aura and 16 healthy controls performed functional magnetic resonance imaging during thermal stimuli (at 41, 51 and 53A degrees C). Patients with migraine showed a greater activation in the perigenual part of anterior cingulate cortex at 51A degrees C and less activation in the bilateral somatosensory cortex at 53A degrees C compared to healthy controls. There were no differences in experimental pain perception between groups. Our findings demonstrate a functional reorganization of cerebral areas known to be involved in pain processing in patients with migraine.

Original language	English
Pages (from-to)	S165-S167
Number of pages	3
Journal	Neurological Sciences
Volume	32
Issue number	S1
DOIs	https://doi.org/10.1007/s10072-011-0537-0
Publication status	Published - May 2011

Keywords

fMRI
Migraine
Pain processing
Anterior cingulate and somatosensory cortices
MECHANISMS
HEADACHE
PAIN

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10.1007/s10072-011-0537-0

Cite this

Tessitore, A., Russo, A., Esposito, F., Giordano, A., Taglialatela, G., De Micco, R., Cirillo, M., Conte, F., d'Onofrio, F., Cirillo, S., & Tedeschi, G. (2011). Interictal cortical reorganization in episodic migraine without aura: an event-related fMRI study during parametric trigeminal nociceptive stimulation. Neurological Sciences, 32(S1), S165-S167. https://doi.org/10.1007/s10072-011-0537-0

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abstract = "The aim of our study was to explore the pain processing network in patients with migraine during trigeminal nociceptive stimulation. Sixteen patients with episodic migraine without aura and 16 healthy controls performed functional magnetic resonance imaging during thermal stimuli (at 41, 51 and 53A degrees C). Patients with migraine showed a greater activation in the perigenual part of anterior cingulate cortex at 51A degrees C and less activation in the bilateral somatosensory cortex at 53A degrees C compared to healthy controls. There were no differences in experimental pain perception between groups. Our findings demonstrate a functional reorganization of cerebral areas known to be involved in pain processing in patients with migraine.",

keywords = "fMRI, Migraine, Pain processing, Anterior cingulate and somatosensory cortices, MECHANISMS, HEADACHE, PAIN",

author = "A. Tessitore and A. Russo and F. Esposito and A. Giordano and G. Taglialatela and {De Micco}, R. and M. Cirillo and F. Conte and F. d'Onofrio and S. Cirillo and G. Tedeschi",

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Tessitore, A, Russo, A, Esposito, F, Giordano, A, Taglialatela, G, De Micco, R, Cirillo, M, Conte, F, d'Onofrio, F, Cirillo, S & Tedeschi, G 2011, 'Interictal cortical reorganization in episodic migraine without aura: an event-related fMRI study during parametric trigeminal nociceptive stimulation', Neurological Sciences, vol. 32, no. S1, pp. S165-S167. https://doi.org/10.1007/s10072-011-0537-0

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T1 - Interictal cortical reorganization in episodic migraine without aura: an event-related fMRI study during parametric trigeminal nociceptive stimulation

AU - Tessitore, A.

AU - Russo, A.

AU - Esposito, F.

AU - Giordano, A.

AU - Taglialatela, G.

AU - De Micco, R.

AU - Cirillo, M.

AU - Conte, F.

AU - d'Onofrio, F.

AU - Cirillo, S.

AU - Tedeschi, G.

PY - 2011/5

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AB - The aim of our study was to explore the pain processing network in patients with migraine during trigeminal nociceptive stimulation. Sixteen patients with episodic migraine without aura and 16 healthy controls performed functional magnetic resonance imaging during thermal stimuli (at 41, 51 and 53A degrees C). Patients with migraine showed a greater activation in the perigenual part of anterior cingulate cortex at 51A degrees C and less activation in the bilateral somatosensory cortex at 53A degrees C compared to healthy controls. There were no differences in experimental pain perception between groups. Our findings demonstrate a functional reorganization of cerebral areas known to be involved in pain processing in patients with migraine.

KW - fMRI

KW - Migraine

KW - Pain processing

KW - Anterior cingulate and somatosensory cortices

KW - MECHANISMS

KW - HEADACHE

KW - PAIN

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DO - 10.1007/s10072-011-0537-0

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