Individual and Neighborhood Deprivation and Carotid Stiffness: The Paris Prospective Study III

Rachel E. Climie*, Pierre Boutouyrie, Marie-Cecile Perier, Catherine Guibout, Thomas T. van Sloten, Frederique Thomas, Nicolas Danchin, James E. Sharman, Stephane Laurent, Xavier Jouven, Jean-Philippe Empana

*Corresponding author for this work

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Abstract

Large artery stiffness is an index of vascular aging associated with cardiovascular mortality. Whereas traditional risk factors for arterial stiffness are known, the contribution of socioeconomic factors is less reported. We sought to determine the relationship between arterial stiffness and socioeconomic deprivation (at the individual and neighborhood levels) in healthy males and females. In 7803 adults, carotid stiffness was determined by high-precision carotid echo-tracking. Individual deprivation data included education, living alone, occupation, and Evaluation of the Deprivation and Inequalities of Health in Healthcare Centers score. Neighborhood deprivation was determined from commune level data (smallest administrative subdivision) available from French National Institute of Statistics and Economic Studies (2011) using principal component analysis. The separate and combined associations between individual and neighborhood deprivation (main exposures) and carotid stiffness (outcome) were quantified using linear and multilevel model adjusted for traditional risk factors. Analyses were conducted separately in males and females. Individual deprivation (lower education and occupation in males and living alone and higher Evaluation of the Deprivation and Inequalities of Health in Healthcare Centers in both populations) was adversely related to carotid stiffness, independently of potential confounders (P

Original languageEnglish
Pages (from-to)1185-1194
Number of pages10
JournalHypertension
Volume73
Issue number6
DOIs
Publication statusPublished - Jun 2019

Keywords

  • aorta
  • blood pressure
  • occupation
  • risk factors
  • socioeconomic factors
  • ALL-CAUSE MORTALITY
  • SOCIOECONOMIC-STATUS
  • ARTERIAL STIFFNESS
  • AORTIC STIFFNESS
  • CARDIOVASCULAR MORTALITY
  • INDEPENDENT PREDICTOR
  • RISK-FACTORS
  • ASSOCIATION
  • MULTILEVEL
  • EXPOSURE

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