Implementing systems medicine within healthcare

M. Kirschner; A. Bauch; A. Agusti; S. Hilke; S. Merk; C. Pison; J. Roldan; B. Seidenath; M. Wilken; E.F. Wouters; H.W. Mewes; K. Heumann; D. Maier

doi:10.1186/s13073-015-0224-5

Implementing systems medicine within healthcare

M. Kirschner^*, A. Bauch, A. Agusti, S. Hilke, S. Merk, C. Pison, J. Roldan, B. Seidenath, M. Wilken, E.F. Wouters, H.W. Mewes, K. Heumann, D. Maier

^*Corresponding author for this work

Research output: Contribution to journal › Editorial › Academic › peer-review

Abstract

The cause of a complex disease cannot be pinpointed to a single origin; rather, a highly complex network of many factors that interact on different levels over time and space is disturbed. This complexity requires novel approaches to diagnosis, treatment, and prevention. To foster the necessary shift to a pro-active systems medicine, proof-of-concept studies are needed. Here, we highlight several systems approaches that have been shown to work within the field of respiratory medicine, and we propose the next steps for broader implementation.

Original language	English
Article number	102
Number of pages	4
Journal	Genome Medicine
Volume	7
Issue number	1
DOIs	https://doi.org/10.1186/s13073-015-0224-5
Publication status	Published - 29 Sept 2015

Keywords

COPD

Access to Document

10.1186/s13073-015-0224-5Licence: CC BY

Cite this

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AU - Kirschner, M.

AU - Bauch, A.

AU - Agusti, A.

AU - Hilke, S.

AU - Merk, S.

AU - Pison, C.

AU - Roldan, J.

AU - Seidenath, B.

AU - Wilken, M.

AU - Wouters, E.F.

AU - Mewes, H.W.

AU - Heumann, K.

AU - Maier, D.

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AB - The cause of a complex disease cannot be pinpointed to a single origin; rather, a highly complex network of many factors that interact on different levels over time and space is disturbed. This complexity requires novel approaches to diagnosis, treatment, and prevention. To foster the necessary shift to a pro-active systems medicine, proof-of-concept studies are needed. Here, we highlight several systems approaches that have been shown to work within the field of respiratory medicine, and we propose the next steps for broader implementation.

KW - COPD

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DO - 10.1186/s13073-015-0224-5

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