Genetic contribution to variation in cognitive function: an FMRI study in twins

J.W. Koten; G. Wood; P. Hagoort; R. Goebel; P. Propping; K. Willmes; D.I. Boomsma

doi:10.1126/science.1167371

Genetic contribution to variation in cognitive function: an FMRI study in twins

J.W. Koten^*, G. Wood, P. Hagoort, R. Goebel, P. Propping, K. Willmes, D.I. Boomsma

^*Corresponding author for this work

Cognitive Neuroscience

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Little is known about the genetic contribution to individual differences in neural networks subserving cognition function. In this functional magnetic resonance imaging (fMRI) twin study, we found a significant genetic influence on brain activation in neural networks supporting digit working memory tasks. Participants activating frontal-parietal networks responded faster than individuals relying more on language-related brain networks. There were genetic influences on brain activation in language-relevant brain circuits that were atypical for numerical working memory tasks as such. This suggests that differences in cognition might be related to brain activation patterns that differ qualitatively among individuals.

Original language	English
Pages (from-to)	1737-1740
Journal	Science
Volume	323
Issue number	5922
DOIs	https://doi.org/10.1126/science.1167371
Publication status	Published - 1 Jan 2009

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10.1126/science.1167371

Cite this

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