TY - JOUR
T1 - Fruit and vegetable intake and cognitive decline in middle-aged men and women: the Doetinchem Cohort Study
AU - Nooyens, A.C.J.
AU - Bueno-de-Mesquita, H.B.
AU - van Boxtel, M.P.J.
AU - van Gelder, B.M.
AU - Verhagen, H.
AU - Verschuren, W.M.M.
PY - 2011/1/1
Y1 - 2011/1/1
N2 - To postpone cognitive decline and dementia in old age, primary prevention is required earlier in life during middle age. Dietary components may be modifiable determinants of mental performance. In the present study, habitual fruit and vegetable intake was studied in association with cognitive function and cognitive decline during middle age. In the Doetinchem Cohort Study, 2613 men and women aged 43-70 years at baseline (1995-2002) were examined for cognitive function twice, with a 5-year time interval. Global cognitive function and the domains memory, information processing speed and cognitive flexibility were assessed. Dietary intake was assessed with a semi-quantitative FFQ. In multivariate linear regression analyses, habitual fruit and vegetable intake was studied in association with baseline and change in cognitive function. Higher reported vegetable intake was associated with lower information processing speed (P=0.02) and worse cognitive flexibility (P=0.03) at baseline, but with smaller decline in information processing speed (P
AB - To postpone cognitive decline and dementia in old age, primary prevention is required earlier in life during middle age. Dietary components may be modifiable determinants of mental performance. In the present study, habitual fruit and vegetable intake was studied in association with cognitive function and cognitive decline during middle age. In the Doetinchem Cohort Study, 2613 men and women aged 43-70 years at baseline (1995-2002) were examined for cognitive function twice, with a 5-year time interval. Global cognitive function and the domains memory, information processing speed and cognitive flexibility were assessed. Dietary intake was assessed with a semi-quantitative FFQ. In multivariate linear regression analyses, habitual fruit and vegetable intake was studied in association with baseline and change in cognitive function. Higher reported vegetable intake was associated with lower information processing speed (P=0.02) and worse cognitive flexibility (P=0.03) at baseline, but with smaller decline in information processing speed (P
U2 - 10.1017/S0007114511001024
DO - 10.1017/S0007114511001024
M3 - Article
C2 - 21477405
SN - 0007-1145
VL - 106
SP - 752
EP - 761
JO - British Journal of Nutrition
JF - British Journal of Nutrition
IS - 5
ER -