Fetal fibronectin status and cervical length in women with threatened preterm labor and the effectiveness of maintenance tocolysis

Carolien Roos*, Jolande Y. Vis, Hubertina C.J. Scheepers, Kitty W. M. Bloemenkamp, Hans J. J. Duvekot, Jim van Eyck, Christianne de Groot, Joke H. Kok, Brent C. Opmeer, Martijn A. Oudijk, Dimitri N. M. Papatsonis, Martina M. Porath, Krystyna Sollie, Marc E. A. Spaanderman, Fred K. Lotgering, Joris A. M. van der Post, Ben Willem J. Mol

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Objective: To assess the effect of maintenance tocolysis in women who are at high or low risk for preterm delivery according to fetal fibronectin (fFN) status and cervical length (CL). Study design: We compared the risk of preterm delivery in fFN pos and fFN neg women and in women with a CL = 15 mm, by using the Cox regression. Differences between the effectiveness of maintenance tocolysis in high- and low-risk women were assessed by using an interaction term. Results: 122 fFN tests were taken, of which 50 were fFN pos. CL was measured in 236 women, of whom 52 women had a CL
Original languageEnglish
Pages (from-to)1556-1561
JournalJournal of Maternal-Fetal & Neonatal Medicine
Volume29
Issue number10
DOIs
Publication statusPublished - 18 May 2016

Keywords

  • fetal fibronectin
  • maintenance tocolysis
  • Cervical length

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