Drugs and Driving Research in Medicinal Drug Development

J. G. Ramaekers

doi:10.1016/j.tips.2017.01.006

Drugs and Driving Research in Medicinal Drug Development

J. G. Ramaekers^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Medicinal drugs that cause drowsiness and inattentiveness may impair driving. The FDA recently emphasized that standardized procedures for measuring drug effects on driving are needed as part of drug registration. Here, I provide an overview of a standardized on-the-road driving test that offers maximal drug sensitivity and uses a real-life outcome measure of driver impairment that is strongly associated with crash risk.

Original language	English
Pages (from-to)	319-321
Journal	Trends in Pharmacological Sciences
Volume	38
Issue number	4
DOIs	https://doi.org/10.1016/j.tips.2017.01.006
Publication status	Published - Apr 2017

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10.1016/j.tips.2017.01.006

Cite this

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title = "Drugs and Driving Research in Medicinal Drug Development",

abstract = "Medicinal drugs that cause drowsiness and inattentiveness may impair driving. The FDA recently emphasized that standardized procedures for measuring drug effects on driving are needed as part of drug registration. Here, I provide an overview of a standardized on-the-road driving test that offers maximal drug sensitivity and uses a real-life outcome measure of driver impairment that is strongly associated with crash risk.",

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