Disease- or Storage-Associated Structural Modifications Are Unlikely to Explain HDL Pro-inflammatory Effects on Macrophages

Emiel P. C. van der Vorst; Kosta Theodorou; Erik A. L. Biessen; Marjo M. P. C. Donners

doi:10.1016/j.cmet.2017.05.017

Disease- or Storage-Associated Structural Modifications Are Unlikely to Explain HDL Pro-inflammatory Effects on Macrophages

Emiel P. C. van der Vorst^*, Kosta Theodorou, Erik A. L. Biessen, Marjo M. P. C. Donners^*

^*Corresponding author for this work

Pathologie

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

Abstract

Van der Vorst et?al. underscore the relevance of HDL quality control, considering HDL source and processing, but argue that disease- or storage-associated structural modifications of HDL cannot explain the observed pro-inflammatory effects on macrophages. Discrepancies between reported effects of HDL in macrophages are probably related to methodological differences.

Original language	English
Pages (from-to)	4-5
Number of pages	2
Journal	Cell Metabolism
Volume	26
Issue number	1
DOIs	https://doi.org/10.1016/j.cmet.2017.05.017
Publication status	Published - 5 Jul 2017

Keywords

SUPPRESS

Access to Document

10.1016/j.cmet.2017.05.017Licence: Free access - publisher

Cite this

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abstract = "Van der Vorst et?al. underscore the relevance of HDL quality control, considering HDL source and processing, but argue that disease- or storage-associated structural modifications of HDL cannot explain the observed pro-inflammatory effects on macrophages. Discrepancies between reported effects of HDL in macrophages are probably related to methodological differences.",

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