Abstract
Aim: To compare health-related quality of life (HRQoL) descriptions and utility scores in newly diagnosed peripheral arterial disease (PAD) patients, using two most widely used instruments, EuroQol 5D (EQ-5D) and Medical Outcome Study 36-item Short-Form Health Status Survey (SF-36). Methods: Patients' self-assessment of HRQoL was measured by the Dutch versions of the EQ-5D and SF-36 in the 204 patients. Results: Mean utility scores ranged from 0.675 for Short-Form Six-Dimension, 0.648 for the EQ-5D UK tariff and 0.715 for the Dutch EQ-5D tariff. A moderate correlation between the utility scores was found due to different valuation techniques of these instruments. Conclusion: Both instruments have clinical validity for use in the PAD and can be used alongside each other to provide a holistic assessment of the HRQoL. Before using these two instruments interchangeably for utility score calculations and healthcare resource allocation, a thorough sensitivity analysis is necessary to explore the robustness of the value argument based on these utility scores.
Original language | English |
---|---|
Pages (from-to) | 535-548 |
Number of pages | 14 |
Journal | Journal of Comparative Effectiveness Research |
Volume | 7 |
Issue number | 6 |
DOIs | |
Publication status | Published - 1 Jun 2018 |
Keywords
- EuroQol 5D
- health-related quality of life
- peripheral arterial disease
- short-form 36
- QUALITY-OF-LIFE
- PERIPHERAL ARTERIAL-DISEASE
- ANKLE BRACHIAL INDEX
- HEALTH-STATUS
- MODELING VALUATIONS
- COST-UTILITY
- EUROQOL
- MANAGEMENT
- COMMUNITY
- AWARENESS