Brown Adipose Tissue: A Human Perspective

M.R. Boon; W.D. van Marken Lichtenbelt

doi:10.1007/164_2015_11

Brown Adipose Tissue: A Human Perspective

M.R. Boon, W.D. van Marken Lichtenbelt

Humane Biologie

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic

Abstract

Since 2009, the presence of brown adipose tissue (BAT) in adult humans has been irrefutably proven. It is estimated that active BAT can contribute up to 2.5-5% of resting metabolic rate in humans, suggesting that sustained activation of BAT may alleviate obesity and associated disorders. In the current chapter, the discovery of BAT in adult humans will be discussed. Furthermore, the characteristics of human BAT, methods to visualize the tissue as well as physiological and pharmacological methods to enhance its activity will be stressed.

Original language	English
Title of host publication	Handbook of Experimental Pharmacology
Publisher	Springer
Pages	301-319
Volume	233
ISBN (Electronic)	978-3-319-29806-1
ISBN (Print)	978-3-319-29804-7
DOIs	https://doi.org/10.1007/164_2015_11
Publication status	Published - 1 Jan 2016

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10.1007/164_2015_11

Cite this

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title = "Brown Adipose Tissue: A Human Perspective",

abstract = "Since 2009, the presence of brown adipose tissue (BAT) in adult humans has been irrefutably proven. It is estimated that active BAT can contribute up to 2.5-5% of resting metabolic rate in humans, suggesting that sustained activation of BAT may alleviate obesity and associated disorders. In the current chapter, the discovery of BAT in adult humans will be discussed. Furthermore, the characteristics of human BAT, methods to visualize the tissue as well as physiological and pharmacological methods to enhance its activity will be stressed.",

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AB - Since 2009, the presence of brown adipose tissue (BAT) in adult humans has been irrefutably proven. It is estimated that active BAT can contribute up to 2.5-5% of resting metabolic rate in humans, suggesting that sustained activation of BAT may alleviate obesity and associated disorders. In the current chapter, the discovery of BAT in adult humans will be discussed. Furthermore, the characteristics of human BAT, methods to visualize the tissue as well as physiological and pharmacological methods to enhance its activity will be stressed.

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