TY - JOUR
T1 - Associations of sedentary time and patterns of sedentary time accumulation with health-related quality of life in colorectal cancer survivors
AU - van Roekel, Eline
AU - Winkler, E.A.
AU - Bours, Martijn
AU - Lynch, B.M.
AU - Willems, Paul
AU - Meijer, Kenneth
AU - Kant, Ijmert
AU - Beets, Geerard
AU - Sanduleanu, Silvia
AU - Healy, G.N.
AU - Weijenberg, Matty
PY - 2016/7
Y1 - 2016/7
N2 - Sedentary behavior (sitting/lying at low energy expenditure while awake) is emerging as an important risk factor that may compromise the health-related quality of life (HRQoL) of colorectal cancer (CRC) survivors. We examined associations of sedentary time with HRQoL in CRC survivors, 2-10?years post-diagnosis. In a cross-sectional study, stage I-III CRC survivors (n?=?145) diagnosed (2002-2010) at Maastricht University Medical Center+, the Netherlands, wore the thigh-mounted MOX activity monitor 24?h/day for seven consecutive days. HRQoL outcomes were assessed by validated questionnaires (EORTC QLQ-C30, WHODAS II, Checklist Individual Strength, and Hospital Anxiety and Depression Scale). Confounder-adjusted linear regression models were used to estimate associations with HRQoL outcomes of MOX-derived total and prolonged sedentary time (in prolonged sedentary bouts ?30?min), and usual sedentary bout duration, corrected for waking wear time. On average, participants spent 10.2?h/day sedentary (SD, 1.6), and 4.5?h/day in prolonged sedentary time (2.3). Mean usual sedentary bout duration was 27.3?min (SD, 16.8). Greater total and prolonged sedentary time, and longer usual sedentary bout duration were associated with significantly (P?
AB - Sedentary behavior (sitting/lying at low energy expenditure while awake) is emerging as an important risk factor that may compromise the health-related quality of life (HRQoL) of colorectal cancer (CRC) survivors. We examined associations of sedentary time with HRQoL in CRC survivors, 2-10?years post-diagnosis. In a cross-sectional study, stage I-III CRC survivors (n?=?145) diagnosed (2002-2010) at Maastricht University Medical Center+, the Netherlands, wore the thigh-mounted MOX activity monitor 24?h/day for seven consecutive days. HRQoL outcomes were assessed by validated questionnaires (EORTC QLQ-C30, WHODAS II, Checklist Individual Strength, and Hospital Anxiety and Depression Scale). Confounder-adjusted linear regression models were used to estimate associations with HRQoL outcomes of MOX-derived total and prolonged sedentary time (in prolonged sedentary bouts ?30?min), and usual sedentary bout duration, corrected for waking wear time. On average, participants spent 10.2?h/day sedentary (SD, 1.6), and 4.5?h/day in prolonged sedentary time (2.3). Mean usual sedentary bout duration was 27.3?min (SD, 16.8). Greater total and prolonged sedentary time, and longer usual sedentary bout duration were associated with significantly (P?
U2 - 10.1016/j.pmedr.2016.06.022
DO - 10.1016/j.pmedr.2016.06.022
M3 - Article
C2 - 27419042
SN - 2211-3355
VL - 4
SP - 262
EP - 269
JO - Preventive Medicine Reports
JF - Preventive Medicine Reports
ER -